ID A0A140L506_9CLOT Unreviewed; 676 AA.
AC A0A140L506;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Methyl-accepting chemotaxis protein McpA {ECO:0000313|EMBL:KXG75631.1};
GN Name=mcpA_1 {ECO:0000313|EMBL:KXG75631.1};
GN ORFNames=AN619_16270 {ECO:0000313|EMBL:KXG75631.1};
OS Thermotalea metallivorans.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Thermotalea.
OX NCBI_TaxID=520762 {ECO:0000313|EMBL:KXG75631.1, ECO:0000313|Proteomes:UP000070456};
RN [1] {ECO:0000313|EMBL:KXG75631.1, ECO:0000313|Proteomes:UP000070456}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B2-1 {ECO:0000313|EMBL:KXG75631.1,
RC ECO:0000313|Proteomes:UP000070456};
RA Patel B.K.;
RT "Draft genome sequence of the thermoanaerobe Thermotalea metallivorans, an
RT isolate from the runoff channel of the Great Artesian Basin, Australia.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG75631.1}.
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DR EMBL; LOEE01000032; KXG75631.1; -; Genomic_DNA.
DR RefSeq; WP_068556218.1; NZ_LOEE01000032.1.
DR AlphaFoldDB; A0A140L506; -.
DR STRING; 520762.AN619_16270; -.
DR PATRIC; fig|520762.4.peg.1805; -.
DR OrthoDB; 1062at2; -.
DR Proteomes; UP000070456; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000070456};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 315..367
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 386..643
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT COILED 639..673
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 676 AA; 73754 MW; F1F03C36A83D95CB CRC64;
MSIRKKLPIL IACFVMISMA ASGIFVYREA SKTILAQSEQ EMLSINTRTI QTIEAVIEKV
QLETKILSKE KEIVQLALAK SSGSEPANQG EIVERIREEL ALKVIDFGGL EYIFAADGKG
VVFASSDETL MGNDYSDRDY MKKSLEGNGA VSQSVIFKSA DQQVLIFSYP ITVNGKTVGV
LGVGVNLGDF YKYLKDIRIG NTKSSYAYLV DKKGIMLSHP DKEKIAKPVE NDTIKKVIYR
LNNGEKIETK VDSYDYKGKQ KVVAYGVIPG TGWVLAVTGD RDEITKPVQN IMEKILWGSV
VIGILVSMIG IFAARQITLP IAKIMEVMGR AAEGDLTVRS HIRRKDELGR LSESFNQMIE
KISDLIQSIQ QTSHGVLASS EALAATTEET SISIEEVAKT VEEVSTGAGN QAKDAEEAVV
AVAALSQELD VIAKNVQESI TVSQNIVRIN QKGLETINGL DRSNMDSTKV SQEVMKVVAE
LSHKANTIGN IVETIANISE QTNLLALNAA IEAARAGDAG RGFAVVAEEV RKLAESTAQS
SKGVQQIIET IRQDIHRAQE TMKAAEHVVK QQNMAVANTR ETFHEIVKTM EGVVENIRRI
AENVDHIGAS KDKVVAVIEN ISAVSEETAA ATQQVSASTE EQTAAMEQVN ALAEELNQLA
QKLEEKIQAF QLSHRE
//
