ID A0A140L5J3_9CLOT Unreviewed; 582 AA.
AC A0A140L5J3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Arginine utilization regulatory protein RocR {ECO:0000313|EMBL:KXG75818.1};
GN Name=rocR_3 {ECO:0000313|EMBL:KXG75818.1};
GN ORFNames=AN619_15720 {ECO:0000313|EMBL:KXG75818.1};
OS Thermotalea metallivorans.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Thermotalea.
OX NCBI_TaxID=520762 {ECO:0000313|EMBL:KXG75818.1, ECO:0000313|Proteomes:UP000070456};
RN [1] {ECO:0000313|EMBL:KXG75818.1, ECO:0000313|Proteomes:UP000070456}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B2-1 {ECO:0000313|EMBL:KXG75818.1,
RC ECO:0000313|Proteomes:UP000070456};
RA Patel B.K.;
RT "Draft genome sequence of the thermoanaerobe Thermotalea metallivorans, an
RT isolate from the runoff channel of the Great Artesian Basin, Australia.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG75818.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LOEE01000031; KXG75818.1; -; Genomic_DNA.
DR RefSeq; WP_068556164.1; NZ_LOEE01000031.1.
DR AlphaFoldDB; A0A140L5J3; -.
DR STRING; 520762.AN619_15720; -.
DR PATRIC; fig|520762.4.peg.1742; -.
DR OrthoDB; 9803970at2; -.
DR Proteomes; UP000070456; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd02205; CBS_pair_SF; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR048106; PrdR-like.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR NCBIfam; NF041552; TF_PrdR; 1.
DR PANTHER; PTHR32071:SF119; SIGMA-54 INTERACTING PROTEIN; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000070456};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 15..71
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 79..135
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 135..183
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 274..503
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 582 AA; 66090 MW; 20EF63AD856E5225 CRC64;
MLENKMLYHR VHEILSANIV KARPTAKVWE VMEAILKENI SEALIEDENE KLVGMITLTD
ISAIMKAGHD LSAPVSNFIQ TDIITVSGNE LISEARKMMI ENKIGRLPVC DGDRIIGIIR
SDNIRDSYYM KLEAINRQYQ HIIDNMHEGV TVTDAAGYVI FWNKSAEKIY DIKAKDILYK
RLVDFFPTAL TLSVLENRTA IENVYHSPKP NYYIIISALP IFIDGEFMGV VATERDVTEY
RNLSVSLEKA NYQINLLKEE MEKITTGGFS LGNIIGKSPI IQEKIQLAKH VSHTDTSVLI
TGESGTGKEV FARSIHYHSK RQGHFVPVNC SAIPHTLFES EFFGYVGGAF TGALKKGKLG
YFELANNGTI FLDEIGDLPL DLQAKLLRVL QEGKVLRIGA EKPIPIDVRV ISATNKNLKA
MVKKGEFRED LYYRLNVVEI ELPPLRDRKE DIILLFDHFL QEICQKNQIK IHHIDREVFD
ILYQYDWKGN IRELRNTVEC MVVLSYDNKI TVESIPQYIM EGAASTINLK RKPSSLDEAL
RASEIDMIRK AMSEAKGNKA KAAQLLNIPR STLYYKLNQY GL
//
