ID A0A140LFS0_DANRE Unreviewed; 153 AA.
AC A0A140LFS0; A0A8M1NZ76;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Si:dkey-241l7.2 {ECO:0000313|Ensembl:ENSDARP00000142094};
GN Name=si:dkey-241l7.2 {ECO:0000313|Ensembl:ENSDARP00000142094,
GN ECO:0000313|RefSeq:NP_001231964.1,
GN ECO:0000313|ZFIN:ZDB-GENE-041014-240};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000142094};
RN [1] {ECO:0000313|RefSeq:NP_001231964.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:NP_001231964.1};
RX PubMed=16630661; DOI=10.1016/j.molimm.2006.03.001;
RA Lin B., Chen S., Cao Z., Lin Y., Mo D., Zhang H., Gu J., Dong M., Liu Z.,
RA Xu A.;
RT "Acute phase response in zebrafish upon Aeromonas salmonicida and
RT Staphylococcus aureus infection: striking similarities and obvious
RT differences with mammals.";
RL Mol. Immunol. 44:295-301(2007).
RN [2] {ECO:0000313|Ensembl:ENSDARP00000142094, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000142094};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:NP_001231964.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:NP_001231964.1};
RX PubMed=27189481;
RA Pasquier J., Cabau C., Nguyen T., Jouanno E., Severac D., Braasch I.,
RA Journot L., Pontarotti P., Klopp C., Postlethwait J.H., Guiguen Y.,
RA Bobe J.;
RT "Gene evolution and gene expression after whole genome duplication in fish:
RT the PhyloFish database.";
RL BMC Genomics 17:368-368(2016).
RN [4] {ECO:0000313|Ensembl:ENSDARP00000142094}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000142094};
RG Ensembl;
RL Submitted (MAR-2016) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001231964.1}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:NP_001231964.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR381646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001231964.1; NM_001245035.1.
DR STRING; 7955.ENSDARP00000142290; -.
DR PaxDb; 7955-ENSDARP00000043687; -.
DR Ensembl; ENSDART00000173215.2; ENSDARP00000142226.1; ENSDARG00000105335.2.
DR Ensembl; ENSDART00000173226.2; ENSDARP00000142290.1; ENSDARG00000105335.2.
DR Ensembl; ENSDART00000173317.2; ENSDARP00000142094.1; ENSDARG00000105335.2.
DR GeneID; 569235; -.
DR KEGG; dre:569235; -.
DR AGR; ZFIN:ZDB-GENE-041014-240; -.
DR ZFIN; ZDB-GENE-041014-240; si:dkey-241l7.2.
DR eggNOG; KOG4297; Eukaryota.
DR OMA; MSWAHAE; -.
DR OrthoDB; 4118525at2759; -.
DR Proteomes; UP000000437; Chromosome 20.
DR Bgee; ENSDARG00000105335; Expressed in tail and 19 other cell types or tissues.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd00037; CLECT; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR002353; AntifreezeII.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR016187; CTDL_fold.
DR PANTHER; PTHR22803:SF141; C-TYPE LECTIN DOMAIN FAMILY 7 MEMBER A-LIKE-RELATED; 1.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR PRINTS; PR00356; ANTIFREEZEII.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A140LFS0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001231964.1}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..153
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001231964.1"
FT /id="PRO_5035035311"
FT DOMAIN 34..147
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
SQ SEQUENCE 153 AA; 17279 MW; 5A92B044BEFCEFD8 CRC64;
MMFLLRSLLL LSIVFSMEGA DEERLRCERG WSGSGSRCFR FFSRSVNWVT AERNCQSLGG
NLASVHDQVE NDFLLSLVPG STRCWIGGHD GEQDGQWLWS DGSVYGYTNW CSGEPSSGSE
HCLEINWTSD RCWNNQGCST RMGYLCAKRR VPC
//
