ID A0A140NM45_PROSM Unreviewed; 260 AA.
AC A0A140NM45;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA polymerase III subunit alpha {ECO:0000256|ARBA:ARBA00019114};
GN Name=dnaE {ECO:0000313|EMBL:AFH94844.1};
GN OrderedLocusNames=S70_15090 {ECO:0000313|EMBL:AFH94844.1};
OS Providencia stuartii (strain MRSN 2154).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1157951 {ECO:0000313|EMBL:AFH94844.1, ECO:0000313|Proteomes:UP000005012};
RN [1] {ECO:0000313|EMBL:AFH94844.1, ECO:0000313|Proteomes:UP000005012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRSN 2154 {ECO:0000313|EMBL:AFH94844.1,
RC ECO:0000313|Proteomes:UP000005012};
RX PubMed=22740665; DOI=10.1128/JB.00615-12;
RA Clifford R.J., Hang J., Riley M.C., Onmus-Leone F., Kuschner R.A.,
RA Lesho E.P., Waterman P.E.;
RT "Complete Genome Sequence of Providencia stuartii Clinical Isolate MRSN
RT 2154.";
RL J. Bacteriol. 194:3736-3737(2012).
RN [2] {ECO:0000313|Proteomes:UP000005012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRSN 2154 {ECO:0000313|Proteomes:UP000005012};
RA Clifford R.J., Hang J., Riley M.C., Onmus-Leone F., Kuschner R.A.,
RA Lesho E.P., Waterman P.E.;
RT "Complete genome sequence of Providencia stuartii clinical isolate MRSN
RT 2154.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP003488; AFH94844.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A140NM45; -.
DR KEGG; psi:S70_15090; -.
DR PATRIC; fig|1157951.4.peg.3040; -.
DR HOGENOM; CLU_001600_4_2_6; -.
DR Proteomes; UP000005012; Chromosome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd07433; PHP_PolIIIA_DnaE1; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR004805; DnaE2/DnaE/PolC.
DR InterPro; IPR004013; PHP_dom.
DR InterPro; IPR003141; Pol/His_phosphatase_N.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR InterPro; IPR049821; PolIIIA_DnaE1_PHP.
DR PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR PANTHER; PTHR32294:SF0; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR Pfam; PF02811; PHP; 1.
DR SMART; SM00481; POLIIIAc; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:AFH94844.1};
KW Transferase {ECO:0000313|EMBL:AFH94844.1}.
FT DOMAIN 7..74
FT /note="Polymerase/histidinol phosphatase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00481"
SQ SEQUENCE 260 AA; 28740 MW; D3FEA1F7325CA769 CRC64;
MAEPRFIHLR VHSDYSMIDG LAKTGPLVKK VAAMGMPAFA ITDFTNLCGL VKFYGAAHGA
GIKPIIGADF FVESEQLGDE IAHLTVLARN NEGYQNLTLL ISEAYQKGYG AIGPTIHRDW
LVKHKEGLIL LSGGRQGDVG QFLLRGNQAL VDECLAFYET HFPGCYYLEL IRTGRPDEES
YLHAAVELAT QRGLPVVATN DVRFIESSDF DAHEIRVAIH DGFTLSDPKR PKNIALSNIY
DLKKRCVSCL PTSLKHLKIV
//
