ID A0A140NNY5_PROSM Unreviewed; 98 AA.
AC A0A140NNY5;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=DNA-binding protein Fis {ECO:0000256|HAMAP-Rule:MF_00166};
GN Name=fis {ECO:0000256|HAMAP-Rule:MF_00166,
GN ECO:0000313|EMBL:AFH94611.1};
GN OrderedLocusNames=S70_13895 {ECO:0000313|EMBL:AFH94611.1};
OS Providencia stuartii (strain MRSN 2154).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1157951 {ECO:0000313|EMBL:AFH94611.1, ECO:0000313|Proteomes:UP000005012};
RN [1] {ECO:0000313|EMBL:AFH94611.1, ECO:0000313|Proteomes:UP000005012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRSN 2154 {ECO:0000313|EMBL:AFH94611.1,
RC ECO:0000313|Proteomes:UP000005012};
RX PubMed=22740665; DOI=10.1128/JB.00615-12;
RA Clifford R.J., Hang J., Riley M.C., Onmus-Leone F., Kuschner R.A.,
RA Lesho E.P., Waterman P.E.;
RT "Complete Genome Sequence of Providencia stuartii Clinical Isolate MRSN
RT 2154.";
RL J. Bacteriol. 194:3736-3737(2012).
RN [2] {ECO:0000313|Proteomes:UP000005012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRSN 2154 {ECO:0000313|Proteomes:UP000005012};
RA Clifford R.J., Hang J., Riley M.C., Onmus-Leone F., Kuschner R.A.,
RA Lesho E.P., Waterman P.E.;
RT "Complete genome sequence of Providencia stuartii clinical isolate MRSN
RT 2154.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC upstream activation of rRNA promoters. {ECO:0000256|HAMAP-
CC Rule:MF_00166}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_00166}.
CC -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC {ECO:0000256|ARBA:ARBA00008559, ECO:0000256|HAMAP-Rule:MF_00166}.
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DR EMBL; CP003488; AFH94611.1; -; Genomic_DNA.
DR RefSeq; WP_004258438.1; NC_017731.1.
DR AlphaFoldDB; A0A140NNY5; -.
DR GeneID; 84571292; -.
DR KEGG; psi:S70_13895; -.
DR PATRIC; fig|1157951.4.peg.2793; -.
DR HOGENOM; CLU_158040_3_0_6; -.
DR OrthoDB; 9802388at2; -.
DR Proteomes; UP000005012; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR HAMAP; MF_00166; DNA_binding_Fis; 1.
DR InterPro; IPR005412; Fis_DNA-bd.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR PANTHER; PTHR47918; DNA-BINDING PROTEIN FIS; 1.
DR PANTHER; PTHR47918:SF1; DNA-BINDING PROTEIN FIS; 1.
DR Pfam; PF02954; HTH_8; 1.
DR PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR PRINTS; PR01591; DNABINDNGFIS.
DR PRINTS; PR01590; HTHFIS.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|HAMAP-Rule:MF_00166};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_00166, ECO:0000313|EMBL:AFH94611.1};
KW Transcription {ECO:0000256|HAMAP-Rule:MF_00166};
KW Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00166}.
FT DOMAIN 55..95
FT /note="DNA binding HTH"
FT /evidence="ECO:0000259|Pfam:PF02954"
FT DNA_BIND 74..93
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00166"
SQ SEQUENCE 98 AA; 11281 MW; 3C29A0FCE2C4F832 CRC64;
MFEQRVNSDV LTVATVNSQD QVTQKPLRDS VKQALKNYFA QLNNQDVNDL YELVLAEVEQ
PLLDMVMQYT RGNQTRAALM MGINRGTLRK KLKKYGMN
//
