ID A0A140SSD7_PROSM Unreviewed; 105 AA.
AC A0A140SSD7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Guanidinium exporter {ECO:0000256|ARBA:ARBA00039168};
GN ORFNames=pMR0211_0060 {ECO:0000313|EMBL:AEZ49672.1};
OS Providencia stuartii (strain MRSN 2154).
OG Plasmid pMR0211 {ECO:0000313|EMBL:AEZ49672.1,
OG ECO:0000313|Proteomes:UP000005012}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1157951 {ECO:0000313|EMBL:AEZ49672.1, ECO:0000313|Proteomes:UP000005012};
RN [1] {ECO:0000313|EMBL:AEZ49672.1, ECO:0000313|Proteomes:UP000005012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRSN 2154 {ECO:0000313|EMBL:AEZ49672.1,
RC ECO:0000313|Proteomes:UP000005012};
RX PubMed=22290972; DOI=10.1128/AAC.05604-11;
RA Mc Gann P., Hang J., Clifford R.J., Yang Y., Kwak Y.I., Kuschner R.A.,
RA Lesho E.P., Waterman P.E.;
RT "Complete sequence of a novel 178-kilobase plasmid carrying bla(NDM-1) in a
RT Providencia stuartii strain isolated in Afghanistan.";
RL Antimicrob. Agents Chemother. 56:1673-1679(2012).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC Gdx/SugE subfamily. {ECO:0000256|ARBA:ARBA00038151}.
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DR EMBL; JN687470; AEZ49672.1; -; Genomic_DNA.
DR RefSeq; YP_005351772.1; NC_016974.1.
DR AlphaFoldDB; A0A140SSD7; -.
DR SMR; A0A140SSD7; -.
DR Proteomes; UP000005012; Plasmid pMR0211.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR000390; Small_drug/metabolite_transptr.
DR InterPro; IPR045324; Small_multidrug_res.
DR PANTHER; PTHR30561:SF0; GUANIDINIUM EXPORTER; 1.
DR PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR Pfam; PF00893; Multi_Drug_Res; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Plasmid {ECO:0000313|EMBL:AEZ49672.1};
KW Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 105 AA; 10897 MW; 62DA129ADA86E765 CRC64;
MSWIVLLIAG LLEVVWAIGL KYTHGFTRLT PSIITIAAMI VSIAMLSWAM RTLPVGTAYA
VWTGIGAVGA AITGILLLGE SASPARLLSL GLIVAGIIGL KLSTH
//
