ID A0A141MJC2_PLARL Unreviewed; 324 AA.
AC A0A141MJC2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Phosphomethylpyrimidine kinase {ECO:0000313|EMBL:ALY06092.1, ECO:0000313|EMBL:CRH00459.1};
DE EC=2.7.4.7 {ECO:0000313|EMBL:CRH00459.1};
DE Flags: Fragment;
GN Name=ThiD {ECO:0000313|EMBL:ALY06092.1};
GN ORFNames=PRELSG_1011300 {ECO:0000313|EMBL:CRH00459.1};
OS Plasmodium relictum.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Haemamoeba).
OX NCBI_TaxID=85471 {ECO:0000313|EMBL:ALY06092.1};
RN [1] {ECO:0000313|EMBL:ALY06092.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SGS1 {ECO:0000313|EMBL:ALY06092.1};
RA Hellgren O., Videvall E.;
RT "De-novo synthesis of Thiamine in Haemosporidian parasites.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CRH00459.1, ECO:0000313|Proteomes:UP000220158}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SGS1 {ECO:0000313|EMBL:CRH00459.1,
RC ECO:0000313|Proteomes:UP000220158};
RG Pathogen Informatics;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KP784834; ALY06092.1; -; mRNA.
DR EMBL; LN835305; CRH00459.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A141MJC2; -.
DR VEuPathDB; PlasmoDB:PRELSG_1011300; -.
DR OMA; DNRHTHG; -.
DR OrthoDB; 5477821at2759; -.
DR Proteomes; UP000220158; Chromosome 10.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 2: Evidence at transcript level;
KW Kinase {ECO:0000313|EMBL:ALY06092.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000220158};
KW Transferase {ECO:0000313|EMBL:CRH00459.1}.
FT DOMAIN 14..297
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT NON_TER 324
FT /evidence="ECO:0000313|EMBL:ALY06092.1"
SQ SEQUENCE 324 AA; 36534 MW; BB8F9201DFE2F658 CRC64;
MMEVTKILSI AGSDSCGGAG MQADIKTATS LGCHCCTVFV VLTSQNTKEV KSIIEIEENF
IIEQLDSIFE DTEINVVKLG VLYSKKIISL VHNYIKNINS KRERKLLVVF DPVFVSSSGC
KLAEDMDYVK FALDMICPIS TIITPNFYEC KLILEVLNCD IDFTNINSIE LCKLFAEKLN
INACLLKSCN IDKNCIEENK LYAVDHLCIR KNKNEIEDIS KKDIININKK GIYIYDIYKL
ITKRTPDADI HGTGCTLSTA ISCFLSKKYD LLYSCIESKK YICNCIKYAY NFGSKSKGLN
HLKASQELLN FNDFEVIKVA QNIS
//
