ID   A0A142CJL8_9VIRU        Unreviewed;      1473 AA.
AC   A0A142CJL8;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:AMQ10630.1};
OS   Brazilian marseillevirus.
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Marseilleviridae; Marseillevirus.
OX   NCBI_TaxID=1813599 {ECO:0000313|EMBL:AMQ10630.1, ECO:0000313|Proteomes:UP000203790};
RN   [1] {ECO:0000313|EMBL:AMQ10630.1, ECO:0000313|Proteomes:UP000203790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BH2014 {ECO:0000313|EMBL:AMQ10630.1,
RC   ECO:0000313|Proteomes:UP000203790};
RX   PubMed=26978387; DOI=10.3390/v8030076;
RA   Dornas F.P., Assis F.L., Aherfi S., Arantes T., Abrahao J.S., Colson P.,
RA   La Scola B.;
RT   "A Brazilian Marseillevirus Is the Founding Member of a Lineage in Family
RT   Marseilleviridae.";
RL   Viruses 8:76-76(2016).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KT752522; AMQ10630.1; -; Genomic_DNA.
DR   RefSeq; YP_009238627.1; NC_029692.1.
DR   GeneID; 27112035; -.
DR   KEGG; vg:27112035; -.
DR   Proteomes; UP000203790; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd13999; STKc_MAP3K-like; 2.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR028081; Leu-bd.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR23257:SF975; DUAL SPECIFICITY PROTEIN KINASE SPLA-RELATED; 1.
DR   PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR   Pfam; PF13458; Peripla_BP_6; 1.
DR   Pfam; PF07714; PK_Tyr_Ser-Thr; 2.
DR   PRINTS; PR00109; TYRKINASE.
DR   SMART; SM00220; S_TKc; 2.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 2.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU10141};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AMQ10630.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000203790};
KW   Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527,
KW   ECO:0000313|EMBL:AMQ10630.1}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          755..1009
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          1220..1467
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          1013..1039
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1013..1033
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         782
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   1473 AA;  162912 MW;  B8086349FA110D76 CRC64;
     MLRGSFFALL FLLSFAQMSQ TQVVISTTAA RSGPAVGIGG LIEGLQTAMF AANNKTTDDR
     NGVLKTRNLE FLVLDDQQDY LQAVNNLQHL FSFPEDELLA ITCLAPMQTA IVQSFPPQVS
     PPPLFGSFSG DVKLYTPFSR NYLNLRPSFD TEFYVMAQFL TSNLRVSRIA FVAGAGLDGT
     SLNFTRSIEP FGLRVVAGHV IPDYTVISGP MMDEAVQIIT SANPQAIVIL LFGPQSAEFI
     RRCKQILPNL VFIIETLVMN DTPNELWLTG DSANVYSLSP FPLLADNNSQ LQNEFYRDQE
     AYFPQWTPAA EQAIEGYVNG RWIISILEKM TGNVTRKNFL ETVFSNPIIK IGEVFFGPLG
     DDCESIIGCC NSATRQMYVF KYPNGYGEYA TEKPISWSSC NPTTLDFQVP TKLGQTLNVS
     EASLRLGIPQ SSGFILLSYD DRGEQQLVKS NIDELERLDN VPLFISLPLE KALLVEKPVF
     GVTPLPQEFK ENFFSVTLSP KEELWAVLQK GIGSSFADPF NSFADFLVAL ESFGKTQGEE
     VVLVVGEKTS VFSKYPGSKF VFLSCLHPEV VVQEATSSGV SMNNILFASS IPFFQVQNIS
     LTQEFTGNSQ AEFWSFVNFK FVQKVASGEF SSSRIETNVW SLLSTDLGGF VIGGYSNVCP
     EGSELECCNK GSRTVFFANG DFGDEGSMNV PFCNAKFSAS STSSSSDNTG AIIGGVIGGV
     AAVLLLCCLF AALVVFLVLS KRERKQEWDI DFAELECSKL IGEGYSGQVF EGTWKGQEVA
     IKVLKSQTPT KKAVEEFKLE ASVLANLRHP NIILFMAACT KPPNMCIITE HMPLGSLFDI
     LHNELIPAFP EGLAIKVATQ AAKGMHFLHS SGIAHRDFKS LNLLVNEKWD VKVSDFGMAS
     FLKDGQVGIG TVFWTAPEIL NEEQNCDLQK ADVYSFGVVL WEMLTRKAPF EGKTPAMVAV
     SVIRDDERPE IPKSSPFDQG YLELMINCWE KDPDARPTFL EVLSRISGLS PIGSSTNKSN
     LSSTSSMDSE RTTRNTGKYP EPDEYVSLAL IDIVDAFSFW EEEPENAREV FTKFNSVCRA
     SAEKYGAYES FVQGMEKGEG CILFVFSSEK SAMFCCEEIF ETLNETSWPG KCRAGIASGC
     VLAKKGIPPV LFGETTEKLK KLCESALPGQ IQVDRVSSCR DFKRIQDSQR IFEEDEGSSV
     KVSGLLSINT SRFVLNFKDI SIGKQIGLGS FGACFAGTWR GVDVCVKRVV DQNMNEDAKL
     RFREEASLLA KFDEHKNIVT FVGACYQKPN ICLVTVLETP GDLGKVLASD ARIDMQTKKK
     ILYGVCSGLG FLHSKNILHR DIKSSNVLVD EQWNAKISDF GFARLKESCA TQTSCGSPCY
     TAPEILRGEK YDEKADIFSL GVLIWEVITR KIPYEGDSPI RVAEKVRDGK RLTVPFDCPK
     RIRKIIQKCW DEFPDQRPSA LEVSLVFAEE EQV
//