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Database: UniProt
Entry: A0A142LMQ1_9PROT
LinkDB: A0A142LMQ1_9PROT
Original site: A0A142LMQ1_9PROT 
ID   A0A142LMQ1_9PROT        Unreviewed;       447 AA.
AC   A0A142LMQ1;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   16-JAN-2019, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AEM42_01730 {ECO:0000313|EMBL:AMS33497.1};
OS   Betaproteobacteria bacterium UKL13-2.
OC   Bacteria; Proteobacteria; Betaproteobacteria.
OX   NCBI_TaxID=1690485 {ECO:0000313|EMBL:AMS33497.1, ECO:0000313|Proteomes:UP000075227};
RN   [1] {ECO:0000313|EMBL:AMS33497.1, ECO:0000313|Proteomes:UP000075227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UKL13-2 {ECO:0000313|EMBL:AMS33497.1};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP012157; AMS33497.1; -; Genomic_DNA.
DR   EnsemblBacteria; AMS33497; AMS33497; AEM42_01730.
DR   KEGG; beb:AEM42_01730; -.
DR   PATRIC; fig|1690485.4.peg.398; -.
DR   KO; K02313; -.
DR   Proteomes; UP000075227; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000075227};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075227}.
FT   DOMAIN      144    280       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      355    424       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     152    159       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   447 AA;  50662 MW;  B34E01EA7640CE96 CRC64;
     MHPFWQACVE DFQHELSPHQ FSTWIKPLRF EQEGDSFVLV APNRFVLQWV KERHLAKIEL
     AAEKFFVRSV MIELAMEEGE DENASLPPDA DERLQTTDAI RPAPNAPTTH RLNPNFTFTS
     FVSGKANQLA RAAAQQVALN PGQAYNPLFV YGATGLGKTH LVQAIGNQLL ERNPKANIKY
     IHAEQFVTDV VRAYQHKAFD SFKRSYHTLD LLLIDDIQFF GNKSRTQEEF FYAFNALIEG
     GKQVVITSDR FPKEISGIED RLISRFGWGL TVSVEPPELE MRVAILMKKA ESEGTPIDEE
     VAFFIAKHIR SNVRELEGGL KRVLAYSRFN NIAVSITSAK EALKDLLAVL NRQISIDNIQ
     KTVADYYKIK VAEMYSKKRV RSLARPRQIA MALAKELTPM SLPEIGEAFG GRDHTTVLHA
     CRKVNELVEA DHMVARDHSL LMQILRG
//
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