ID A0A142MEE5_AMIAI Unreviewed; 1020 AA.
AC A0A142MEE5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:MBB3704492.1};
DE EC=1.5.3.1 {ECO:0000313|EMBL:MBB3704492.1};
GN ORFNames=FHS67_000795 {ECO:0000313|EMBL:MBB3704492.1};
OS Aminobacter aminovorans (Chelatobacter heintzii).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Aminobacter.
OX NCBI_TaxID=83263 {ECO:0000313|EMBL:MBB3704492.1, ECO:0000313|Proteomes:UP000577697};
RN [1] {ECO:0000313|EMBL:MBB3704492.1, ECO:0000313|Proteomes:UP000577697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10368 {ECO:0000313|EMBL:MBB3704492.1,
RC ECO:0000313|Proteomes:UP000577697};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MBB3704492.1}.
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DR EMBL; JACICB010000002; MBB3704492.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A142MEE5; -.
DR Proteomes; UP000577697; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:MBB3704492.1}.
FT DOMAIN 534..618
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 634..899
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 927..1012
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 1020 AA; 109861 MW; 2DB7C22CD860EA75 CRC64;
MSGYSGSEPL GRTAALEGAP TSARSQAASA SQSHRLRSGG LIDRQQPLQF SFDGKVMSGF
AGDTLASALV ANGVKLVARS FKYHRPRGII TAGSEEPSAL VEMRSGARKE PNTRATTQEL
YDGLVAQSQN RWPSLRRDFM SINQLAAPIF VAGFYYKTFM WPAKFWEKVY EPLIRRAAGL
GKSAELPDPD HYDKAWAHCD VLVIGGGAAG LSAALAAGRA GSRVILVEED SRLGGRLLSD
GGEIDGMHAE EWVRRTTDEL TALPNVRIMV RTALFGVYDG GVYAALERVN DHVPVPGPHQ
VRQRVWRIVA KRSVVTAGAI ERPIVFPGND RPGVMMASAV RTYVHRFAAM PGRKVALFTN
NDDGWRTVEA IQQAGGDIAA VIDPRGKVPA EYQALAELSD LRVLSGGVSD VKGGVDGVRG
VVVTDGNGRT QQIDADCLAV SGGWNPNVGL SCFHRGRPVW RDDIAAFVPG DSPKGMTTAG
AANGEFSLGA CLRDGHAAGA AAAAECGASG NAGEASEAGD EVYAISPLWQ VKAKGKAFVD
FQHDVTASDV TLAQREGFES VEHLKRYTTL GMATDQGKTS NITGLAIMAE ATGRTIPQTG
TTIYRPPYAP VAIGALAGHH RDENFHAWRL TPSHHWAAAR GAVFVDTGLW KRAQWYPQPG
EKDWLESVTR EVLAVRNGVG FCDVSTLGKV DVRGADAGTF LDRVYINAFS SLAVGKARYG
LMLREDGIVM DDGTTSRIAE DHYFLTTTTA KAGPVMAHLE FCRQVLWPEL DVQLSSASDQ
WAQFSIAGPN TRKLLQELVD PSEDMSNEGF PFMGAREVKL RGGVTARLFR ISFSGEIAFE
ISVPARYGAA MAQNLMIAGR DLGVTPYGTE ALGVMRIEKG HVAGPELNGT TTADDLGLGK
MMSKKKDFIG RVMAGREALT APDRQVVVGI KPLDQKRRLR SGAHVVPKGA IPGPETDQGY
VTSVCYSPML EQWIGLGLVE RGRERFGEVV RIHDPLRSED YEAEICNPVF YDPEGARQRG
//
