ID A0A142XNL4_9BACT Unreviewed; 399 AA.
AC A0A142XNL4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=inositol-3-phosphate synthase {ECO:0000256|ARBA:ARBA00012125};
DE EC=5.5.1.4 {ECO:0000256|ARBA:ARBA00012125};
GN Name=ino1 {ECO:0000313|EMBL:AMV28282.1};
GN ORFNames=VT84_28015 {ECO:0000313|EMBL:AMV28282.1};
OS Gemmata sp. SH-PL17.
OC Bacteria; Planctomycetota; Planctomycetia; Gemmatales; Gemmataceae;
OC Gemmata.
OX NCBI_TaxID=1630693 {ECO:0000313|EMBL:AMV28282.1, ECO:0000313|Proteomes:UP000076098};
RN [1] {ECO:0000313|EMBL:AMV28282.1, ECO:0000313|Proteomes:UP000076098}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH-PL17 {ECO:0000313|EMBL:AMV28282.1,
RC ECO:0000313|Proteomes:UP000076098};
RA van der Voort M., Raaijmakers J.M.;
RT "Genome minning of novel planctomycete species.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- PATHWAY: Polyol metabolism; myo-inositol biosynthesis; myo-inositol
CC from D-glucose 6-phosphate: step 1/2. {ECO:0000256|ARBA:ARBA00005117}.
CC -!- SIMILARITY: Belongs to the myo-inositol 1-phosphate synthase family.
CC {ECO:0000256|ARBA:ARBA00010813}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP011271; AMV28282.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A142XNL4; -.
DR STRING; 1630693.VT84_28015; -.
DR KEGG; ges:VT84_28015; -.
DR PATRIC; fig|1630693.3.peg.5959; -.
DR OrthoDB; 729130at2; -.
DR Proteomes; UP000076098; Chromosome.
DR GO; GO:0004512; F:inositol-3-phosphate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006021; P:inositol biosynthetic process; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002587; Myo-inos-1-P_Synthase.
DR InterPro; IPR013021; Myo-inos-1-P_Synthase_GAPDH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR11510:SF5; INOSITOL-3-PHOSPHATE SYNTHASE 1; 1.
DR PANTHER; PTHR11510; MYO-INOSITOL-1 PHOSPHATE SYNTHASE; 1.
DR Pfam; PF01658; Inos-1-P_synth; 1.
DR Pfam; PF07994; NAD_binding_5; 1.
DR PIRSF; PIRSF015578; Myoinos-ppht_syn; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:AMV28282.1};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000076098}.
FT DOMAIN 237..341
FT /note="Myo-inositol-1-phosphate synthase GAPDH-like"
FT /evidence="ECO:0000259|Pfam:PF01658"
SQ SEQUENCE 399 AA; 43330 MW; 3C16020A90BB9474 CRC64;
MAQRRVGLWL IGACGGVAST TALGLSALAR GHTPTTGMVT ALPQFRGHDF DEPAAFVLGG
HDIRKGNFVT AARELHERSN VFDERTLAAC VGDLETWSAN IRPGVVYRPN AAITALADRG
DMRRANTARE AIDAIQGDLK AFKAANKLDQ VVVVNAASTE PPFEATDEQK SLELLVPALD
RPAPAALPTS GVYAFAAIDA GLPYVNMTPS RGATLPAIEE LARKRGVPHA GQDLKTGETL
IKSVLAPMFA RRNLRVLSWV GHNILGNRDG QVLNDPDNKA SKVKSKDLLL AELLGYKPQS
HVSIEYIESL DDWKTAWDHI HFEGFLGTKM MMQFTWQGCD SLLAAPLVID LVRLAALAQR
RGESGPMPHT ACFFKSPVGV TEHDFGKQFQ MLEDYLTAR
//
