ID A0A142XVY9_9BACT Unreviewed; 366 AA.
AC A0A142XVY9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN Name=dnaA_2 {ECO:0000313|EMBL:AMV30994.1};
GN ORFNames=VN12_02685 {ECO:0000313|EMBL:AMV30994.1};
OS Pirellula sp. SH-Sr6A.
OC Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC Pirellula.
OX NCBI_TaxID=1632865 {ECO:0000313|EMBL:AMV30994.1, ECO:0000313|Proteomes:UP000076398};
RN [1] {ECO:0000313|EMBL:AMV30994.1, ECO:0000313|Proteomes:UP000076398}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH-Sr6A {ECO:0000313|EMBL:AMV30994.1,
RC ECO:0000313|Proteomes:UP000076398};
RA van der Voort M., Raaijmakers J.M.;
RT "Genome minning of novel planctomycete species.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays an important role in the initiation and regulation of
CC chromosomal replication. Binds to the origin of replication; it binds
CC specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-
CC TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
CC {ECO:0000256|RuleBase:RU000577}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|ARBA:ARBA00006583,
CC ECO:0000256|RuleBase:RU004227}.
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DR EMBL; CP011272; AMV30994.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A142XVY9; -.
DR STRING; 1632865.VN12_02685; -.
DR KEGG; pir:VN12_02685; -.
DR PATRIC; fig|1632865.3.peg.589; -.
DR OrthoDB; 9807019at2; -.
DR Proteomes; UP000076398; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd06571; Bac_DnaA_C; 1.
DR Gene3D; 1.10.1750.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR InterPro; IPR013317; DnaA.
DR InterPro; IPR013159; DnaA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010921; Trp_repressor/repl_initiator.
DR PANTHER; PTHR30050; CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA; 1.
DR PANTHER; PTHR30050:SF2; CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA; 1.
DR Pfam; PF00308; Bac_DnaA; 1.
DR Pfam; PF08299; Bac_DnaA_C; 1.
DR PRINTS; PR00051; DNAA.
DR SMART; SM00760; Bac_DnaA_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48295; TrpR-like; 1.
DR PROSITE; PS01008; DNAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000577};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU000577};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU000577};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000577};
KW Reference proteome {ECO:0000313|Proteomes:UP000076398}.
FT DOMAIN 274..343
FT /note="Chromosomal replication initiator DnaA C-terminal"
FT /evidence="ECO:0000259|SMART:SM00760"
SQ SEQUENCE 366 AA; 40571 MW; A7FED761A132A520 CRC64;
MAMPASADPL TSLAIHSPRP RKNSTLILPG FKPLLDSFLI GPENEALREL SQATSIAKLH
ERSPLLLLGS SGVGKTAVAM TLATRWINDA PNRTYAIVSA LDFARSMVLA IESDDMPRFR
EQYRQVSCLV IDNAHELSGK EGSQNELIEV LNAHEGQDSL VILTSLTLPA FIPGWNHALA
SRMIAGYSLE LQHPGATTRS ELIKRLSDAQ SLPISEEERN EINSQLGDNQ SLHQLQGLLL
RWRHHHRAHE GRVKPNKSKV IESLVESQTP SPKTPLEIAK SVAREMRQTM EAMRGPSRKA
SVVRARGLAM HLIREWTDAS YQAIGGLFGD RDHTTVMHAC KKIEDAIASD PELLRCIDRV
RQKLLP
//
