ID A0A142YH01_9PLAN Unreviewed; 318 AA.
AC A0A142YH01;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Glycerate dehydrogenase {ECO:0000313|EMBL:AMV38521.1};
DE EC=1.1.1.29 {ECO:0000313|EMBL:AMV38521.1};
GN Name=hprA_2 {ECO:0000313|EMBL:AMV38521.1};
GN ORFNames=VT85_13880 {ECO:0000313|EMBL:AMV38521.1};
OS Planctomyces sp. SH-PL62.
OC Bacteria; Planctomycetota; Planctomycetia; Planctomycetales;
OC Planctomycetaceae; Planctomyces.
OX NCBI_TaxID=1636152 {ECO:0000313|EMBL:AMV38521.1, ECO:0000313|Proteomes:UP000076365};
RN [1] {ECO:0000313|EMBL:AMV38521.1, ECO:0000313|Proteomes:UP000076365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH-PL62 {ECO:0000313|EMBL:AMV38521.1,
RC ECO:0000313|Proteomes:UP000076365};
RA van der Voort M., Raaijmakers J.M.;
RT "Genome minning of novel planctomycete species.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; CP011273; AMV38521.1; -; Genomic_DNA.
DR RefSeq; WP_068416066.1; NZ_CP011273.1.
DR AlphaFoldDB; A0A142YH01; -.
DR STRING; 1636152.VT85_13880; -.
DR KEGG; plh:VT85_13880; -.
DR PATRIC; fig|1636152.3.peg.3158; -.
DR OrthoDB; 277029at2; -.
DR Proteomes; UP000076365; Chromosome.
DR GO; GO:0008465; F:glycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR CDD; cd12162; 2-Hacid_dh_4; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000076365}.
FT DOMAIN 21..317
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 107..287
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 318 AA; 33667 MW; 522789EB756D3005 CRC64;
MKIVVLDGRT LNDDPKAWAG LAPFGEVAYH DVTEPDEVLE RASGAEVLIV NKCAIRRDVI
AGLPDLRFIA VTATGFDCVD VEAARERGIV VSNVRGYSTD SVAQVTFALL LELTLHVGLH
SDAVFAGEWA AQPDFSIRKT PLIELAGKTI AIVGLGQIGR RVAGIAQAFG MNVVAHRPSG
KPADPNDPIP ALTLEEAFER ADVVSLHCPL TPTTQGMVSR ERLARAKPSA FLINTGRGAL
VVERDLADAL NEGVIAGAAV DVVTREPIAP DNPLLKAKNC IITPHIAWAT AEARERLMAA
TVENVAAYAA GKPINVVG
//
