ID A0A143WZZ5_9FIRM Unreviewed; 139 AA.
AC A0A143WZZ5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Mini-ribonuclease 3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE Short=Mini-3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE Short=Mini-RNase 3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE EC=3.1.26.- {ECO:0000256|HAMAP-Rule:MF_01468};
DE AltName: Full=Mini-RNase III {ECO:0000256|HAMAP-Rule:MF_01468};
DE Short=Mini-III {ECO:0000256|HAMAP-Rule:MF_01468};
GN Name=mrnC {ECO:0000256|HAMAP-Rule:MF_01468,
GN ECO:0000313|EMBL:CVH75970.1};
GN ORFNames=BN3662_01285 {ECO:0000313|EMBL:CVH75970.1};
OS Clostridiales bacterium CHKCI006.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1780379 {ECO:0000313|EMBL:CVH75970.1, ECO:0000313|Proteomes:UP000198633};
RN [1] {ECO:0000313|EMBL:CVH75970.1, ECO:0000313|Proteomes:UP000198633}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHKC6 {ECO:0000313|EMBL:CVH75970.1};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in correct processing of both the 5' and 3' ends of
CC 23S rRNA precursor. Processes 30S rRNA precursor transcript even in
CC absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller
CC rRNA precursors. {ECO:0000256|HAMAP-Rule:MF_01468}.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01468};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01468}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01468}.
CC -!- SIMILARITY: Belongs to the MrnC RNase family. {ECO:0000256|HAMAP-
CC Rule:MF_01468}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FCNA01000065; CVH75970.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A143WZZ5; -.
DR STRING; 1780379.BN3662_01285; -.
DR OrthoDB; 46571at2; -.
DR Proteomes; UP000198633; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 1.
DR HAMAP; MF_01468; RNase_Mini_III; 1.
DR InterPro; IPR008226; Mini3_fam.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR34276; MINI-RIBONUCLEASE 3; 1.
DR PANTHER; PTHR34276:SF1; MINI-RIBONUCLEASE 3; 1.
DR Pfam; PF00636; Ribonuclease_3; 1.
DR PIRSF; PIRSF005520; UCP005520; 1.
DR SUPFAM; SSF69065; RNase III domain-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01468};
KW Endonuclease {ECO:0000256|HAMAP-Rule:MF_01468};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_01468};
KW Magnesium {ECO:0000256|HAMAP-Rule:MF_01468};
KW Nuclease {ECO:0000256|HAMAP-Rule:MF_01468};
KW Reference proteome {ECO:0000313|Proteomes:UP000198633};
KW Ribosome biogenesis {ECO:0000256|HAMAP-Rule:MF_01468};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_01468};
KW rRNA processing {ECO:0000256|HAMAP-Rule:MF_01468};
KW rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01468}.
FT DOMAIN 10..108
FT /note="RNase III"
FT /evidence="ECO:0000259|Pfam:PF00636"
FT ACT_SITE 16
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01468"
SQ SEQUENCE 139 AA; 16118 MW; EBC9E2CD6E53CEF9 CRC64;
MRPELTNALV LAYIGDAVLE VLVRDYLVLE AGIVKPHLLQ KASIQYVSAW AQADFMQAAK
EQGWLTSQEL DWYRRGRNAH HARKTHKDVK AHNESSGFEA ILGTWHLMGN EPRIQEIFRL
YIAYINRKKG ETDERMDLR
//
