ID A0A143X466_9FIRM Unreviewed; 300 AA.
AC A0A143X466;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=(S)-sulfolactate dehydrogenase {ECO:0000313|EMBL:CVH77418.1};
DE EC=1.1.1.310 {ECO:0000313|EMBL:CVH77418.1};
GN Name=slcC {ECO:0000313|EMBL:CVH77418.1};
GN ORFNames=BN3662_02178 {ECO:0000313|EMBL:CVH77418.1};
OS Clostridiales bacterium CHKCI006.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1780379 {ECO:0000313|EMBL:CVH77418.1, ECO:0000313|Proteomes:UP000198633};
RN [1] {ECO:0000313|EMBL:CVH77418.1, ECO:0000313|Proteomes:UP000198633}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHKC6 {ECO:0000313|EMBL:CVH77418.1};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FCNA01000112; CVH77418.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A143X466; -.
DR STRING; 1780379.BN3662_02178; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000198633; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0102155; F:S-sulfolactate dehydrogenase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000198633}.
FT DOMAIN 12..298
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 105..276
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 300 AA; 34014 MW; 4DEF74CCF54B8168 CRC64;
MNLLVTGSFS WEKDEINILK DLGHEIIFMQ QETDDLPCAP EWVEGIIGNG ILLKHPIQQF
TSLQYIQLTS AGYDRVPMEY IKNNKIRIFN AMGVYSVPMA EFAVMSVLQL LKHSKFFLEN
QKEHKWIKNR NIIELSEKIV CIVGCGNVGT ECAKRFSSFC CKVIGVDSSP YQSEYFETIL
HMNDFEQALS ISDVVILTLP LTEDTRGMMD AKRFSVMKDG AILVNIARGP IVKTDDLISA
LNNKLGGAVL DVFEEEPLSK KSILWDLKSV IITPHNSFVG DGNHKRMFKI IFNNLRSWSI
//
