ID A0A143XB44_9ACTN Unreviewed; 936 AA.
AC A0A143XB44;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Glucokinase {ECO:0000313|EMBL:CVH80231.1};
DE EC=2.7.1.2 {ECO:0000313|EMBL:CVH80231.1};
GN Name=glcK {ECO:0000313|EMBL:CVH80231.1};
GN ORFNames=BN3658_02796 {ECO:0000313|EMBL:CVH80231.1};
OS Coriobacteriaceae bacterium CHKCI002.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales;
OC Coriobacteriaceae.
OX NCBI_TaxID=1780377 {ECO:0000313|EMBL:CVH80231.1, ECO:0000313|Proteomes:UP000199067};
RN [1] {ECO:0000313|Proteomes:UP000199067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Millard A.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FCNB01000256; CVH80231.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A143XB44; -.
DR STRING; 1780377.BN3658_02796; -.
DR OrthoDB; 9810372at2; -.
DR Proteomes; UP000199067; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004340; F:glucokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR18964:SF177; N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF00480; ROK; 1.
DR PRINTS; PR01333; 2POREKCHANEL.
DR PRINTS; PR00169; KCHANNEL.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS01125; ROK; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CVH80231.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199067};
KW Transferase {ECO:0000313|EMBL:CVH80231.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..238
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 470..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 936 AA; 96979 MW; 6CADD333DD9E40FF CRC64;
MRERIFNIVQ RARPGDVVSH AYDVFIVAVA FLSIVPLMFR PQDMTPQMAV VLNMIDVVTV
YLLFLDYILR WMTHDFKVGK TGKLGKGGWR VFARYPFTPL AIIDMLAILP SLGVLPESLK
FLRVLRVTKM FRYSKNLTIV ANVFRAQRNT LLSVLAVALM YIFVSGLVMF VNEPNTFDNF
FDALYWATTA LTTVGYGDVY PVTDLGKFIS MASSLFGIAV IALPAGIITG GFLEQVRQRD
EDAEAYFRAD ERDPFKGRTP FSYESVRAWA KAHPKAVAYG VTMLACVLVN EALYFAALAL
GAPVWLDTVG TALAAVLLEP AAALIVGFAN NLVLAVQFGN AGNLLYYALS AITALVYGTV
FARGRRITAR SLGWAALFLV VVEALISTVL TFSLAGGQLT TAAEQLYGSV LRGLGAPEAA
AVFGALLVDK LADTVVVFAV AMGAVRLVVG SRLDPARWFS RSVVRAKGEE SAEARTGADD
EAGTGVGASS DAEAPGGVCA EVRAFGDAGA CAGAGASGPA VGVASVVTAR ACEAGSAEAA
GSTGSAGSAG SAGVAGSASA AEGVGAVGAA AGIGASGTAG DFGVESAAVT AIPSADAVGV
ATASAAVAPE CVERYVLGID VGGTHTKAGV FDLAGSRVAS HAFGSQSVLA DGSHVRLSRE
MRALLDQAGI DGRSVVGVGL AVPGAVAAEE SLTLCPHIDL DLRSYKSLLL ELFPRARVAV
LNDADAAVLG DRWRGTSHDR QCENVALVTL GTGVGAGVVV RGRLLSGVHG AAGEVGHLCV
NPSEEERCSC GKAGCLEQYA SATGLVRHAR AALLAAGDVA SSDQAADVFP DARAVLDAVE
RRDPHARAAL DRFSDALGFG LAQMACFADP DVFVLGGGLS ERADLFIDAV RSRYRSCAVS
ACRDTPVVAS SLGNECGVYG AAYRALQTLK DEGGLA
//
