ID A0A143XKC3_9FIRM Unreviewed; 554 AA.
AC A0A143XKC3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Alpha-amylase {ECO:0000256|RuleBase:RU361134};
DE EC=3.2.1.1 {ECO:0000256|RuleBase:RU361134};
GN Name=malL_1 {ECO:0000313|EMBL:CVI67572.1};
GN ORFNames=NDGK_00924 {ECO:0000313|EMBL:CVI67572.1};
OS Clostridiales bacterium CHKCI001.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1780378 {ECO:0000313|EMBL:CVI67572.1, ECO:0000313|Proteomes:UP000198774};
RN [1] {ECO:0000313|EMBL:CVI67572.1, ECO:0000313|Proteomes:UP000198774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHKC1 {ECO:0000313|EMBL:CVI67572.1};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in
CC polysaccharides containing three or more (1->4)-alpha-linked D-
CC glucose units.; EC=3.2.1.1; Evidence={ECO:0000256|RuleBase:RU361134};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC {ECO:0000256|ARBA:ARBA00008061, ECO:0000256|RuleBase:RU003615}.
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DR EMBL; FCNS01000012; CVI67572.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A143XKC3; -.
DR STRING; 1780378.NDGK_00924; -.
DR OrthoDB; 9805159at2; -.
DR Proteomes; UP000198774; Unassembled WGS sequence.
DR GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043169; F:cation binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd11333; AmyAc_SI_OligoGlu_DGase; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR006046; Alpha_amylase.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR045857; O16G_dom_2.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF179; NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR PRINTS; PR00110; ALPHAAMYLASE.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361134};
KW Glycosidase {ECO:0000256|RuleBase:RU361134, ECO:0000313|EMBL:CVI67572.1};
KW Hydrolase {ECO:0000256|RuleBase:RU361134, ECO:0000313|EMBL:CVI67572.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198774}.
FT DOMAIN 13..417
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
SQ SEQUENCE 554 AA; 64474 MW; 4FE616F42C6C224D CRC64;
MQKKWWQEEI VYQIYPKSFC DSNGDGIGDI NGIISKLDYL KNLGVTMLWI CPIFQSPMDD
NGYDISNYFA LAPEFGSMEE LRNLVKLAKE KGIKIILDLV INHTSDEHEW FQEALKDPNS
KYHDFYIFKS GTEVPNNWRS MFGGSVWEKV EGRDEFYYHS FGKKQPDLNW ENKEVRETLY
QMVNQWLDFG IAGFRVDAIT FIKKDLTFQS READGVDGLV KCTKTSRNQP GIETFLRELK
EQTFQKHDCV TVAEAPGVQY EELEDFIGED GYFSMIFDFK HADLDIASGS EWFKRIPWTI
KDLRDRLMTS QLAIQKVGWS ANFIENHDQP RATSKYLLDQ EANLDAVKTL GAMYFFLRGT
PFIYQGQELG MRNFTRSGIE EFNDISSIDQ YYRSIEEGCT EEEALHYINL RSRDNARTPF
PWKNTENAGF SSGKPWLKVT EHYSEINAND QVQNPDSIYH FYRHLIDLRQ NSDFKECLIY
GDIIPLETQC QDVIAYIRKT EKETIGCYFS FSKEVQKELL PAEVSEIVLS TKTAIYKEKE
VSLAPFQTFM AVIK
//
