ID A0A143XKT4_9BACT Unreviewed; 415 AA.
AC A0A143XKT4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Hemolysin C {ECO:0000313|EMBL:CVI68460.1};
GN Name=tlyC_1 {ECO:0000313|EMBL:CVI68460.1};
GN ORFNames=BN3659_01184 {ECO:0000313|EMBL:CVI68460.1};
OS Alistipes sp. CHKCI003.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae;
OC Alistipes.
OX NCBI_TaxID=1780376 {ECO:0000313|EMBL:CVI68460.1, ECO:0000313|Proteomes:UP000198813};
RN [1] {ECO:0000313|EMBL:CVI68460.1, ECO:0000313|Proteomes:UP000198813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHKC3 {ECO:0000313|EMBL:CVI68460.1};
RA Oliw E.H.;
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FCNT01000050; CVI68460.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A143XKT4; -.
DR STRING; 1780376.BN3659_01184; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000198813; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR019862; Motility-assoc_prot_GldE.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR NCBIfam; TIGR03520; GldE; 1.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF17; UPF0053 INNER MEMBRANE PROTEIN YFJD; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000198813};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..415
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007514250"
FT TRANSMEM 60..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..183
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 202..261
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 266..323
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 415 AA; 46514 MW; 05202730DD9E0CE3 CRC64;
MSPRIAVMCA AACCLLLVSA LVSGAETAFF SLSRSDVRRI REQKSASAEA VLFLLKNVDM
LLATILVVNN LVNICIVILA SGIIDSIFTF RRFEFLFKTV LVTFLLLLFG EILPKVLAQT
MHVRFACLVA RPIRVLRWLF YPISYLLVNT GSRISEKAAH KSEISLDELA DAVDMTQTTS
HEEHEILSGI VNFVNTEAVE IMKPRMDITA VNITDSYGKV KDSIIRSGFS RIPVYEGEID
NIRGTLYVKD LLPYIDRGDE FGWQQLIRKS YFVPGNKKIS DLLEDFQANK VHMAIVVDEY
GSTLGLVSLE DIIEEIVGEI SDESDMDETF YKRLDETTYL FDGKTHIGDF ERVLSLGEET
FSDVKGEAET LGGLILELKR DFPAKGDTFT AHGIDFTVES LDGRRVDKLR VVLHG
//
