ID   A0A143YJ31_9LACT        Unreviewed;       447 AA.
AC   A0A143YJ31;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   ORFNames=TR210_814 {ECO:0000313|EMBL:CZQ89639.1};
OS   Trichococcus ilyis.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC   Trichococcus.
OX   NCBI_TaxID=640938 {ECO:0000313|EMBL:CZQ89639.1, ECO:0000313|Proteomes:UP000076878};
RN   [1] {ECO:0000313|EMBL:CZQ89639.1, ECO:0000313|Proteomes:UP000076878}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Trichococcus_R210 {ECO:0000313|EMBL:CZQ89639.1};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FJNB01000004; CZQ89639.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A143YJ31; -.
DR   STRING; 640938.TR210_814; -.
DR   Proteomes; UP000076878; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF10; PERMEASE IIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351}; Transferase {ECO:0000313|EMBL:CZQ89639.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        20..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        75..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        147..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        364..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          6..420
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   447 AA;  48417 MW;  2287C2BB41471FD9 CRC64;
     MENAKWIERL NMIAYKINDL KYIIAIKNAF SMLLPVIITG AFATLFSNMV FDPINGLAQF
     EALRFLEQMK PITQAINYAT MNLMTIGAVF LIGIEVAKLN KVSDHFAGLL AVISYIATIP
     TAIEVLFEET PVPVTNVLSS NYTGSRGLFL GMFIAIVSVE LYTWLSKQEK LKISMPDTVP
     TNVSRGFSAL IPTILTVSII AAGAHLIFMI TGLTLYDIIY TTIQAPLAKV VQGLPGILLL
     MFVSQIFWVI GIHGNQMIKP IREPILLAAI AENTAAFEAG KEVPHIINMP FWDMYMSMGG
     SGVTIGLLIA VFLVSKRADF KEIGKLSVGP GIFNINEPLI FGMPIMLNPI MAIPFILTPL
     VTGTIGYFAT AIGFAGKAVV MVPWTTPPLI SGYLATAGSL GAVATQLICI VVSALIYLPF
     VKASNRALAV DTEAETERKT ETATAVE
//