ID A0A143Z8B0_9LACT Unreviewed; 510 AA.
AC A0A143Z8B0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Citrate lyase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE Short=Citrase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE EC=2.8.3.10 {ECO:0000256|PIRNR:PIRNR009451};
DE EC=4.1.3.6 {ECO:0000256|PIRNR:PIRNR009451};
DE AltName: Full=Citrate (pro-3S)-lyase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE AltName: Full=Citrate CoA-transferase subunit {ECO:0000256|PIRNR:PIRNR009451};
GN ORFNames=TR210_2846 {ECO:0000313|EMBL:CZR10033.1};
OS Trichococcus ilyis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Trichococcus.
OX NCBI_TaxID=640938 {ECO:0000313|EMBL:CZR10033.1, ECO:0000313|Proteomes:UP000076878};
RN [1] {ECO:0000313|EMBL:CZR10033.1, ECO:0000313|Proteomes:UP000076878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Trichococcus_R210 {ECO:0000313|EMBL:CZR10033.1};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + citrate = (3S)-citryl-CoA + acetate;
CC Xref=Rhea:RHEA:19405, ChEBI:CHEBI:16947, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57288, ChEBI:CHEBI:57321; EC=2.8.3.10;
CC Evidence={ECO:0000256|PIRNR:PIRNR009451};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=citrate = acetate + oxaloacetate; Xref=Rhea:RHEA:10760,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:30089; EC=4.1.3.6;
CC Evidence={ECO:0000256|PIRNR:PIRNR009451};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR009451}.
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DR EMBL; FJNB01000031; CZR10033.1; -; Genomic_DNA.
DR RefSeq; WP_068624831.1; NZ_FNYT01000034.1.
DR AlphaFoldDB; A0A143Z8B0; -.
DR STRING; 640938.TR210_2846; -.
DR OrthoDB; 9767643at2; -.
DR Proteomes; UP000076878; Unassembled WGS sequence.
DR GO; GO:0009346; C:ATP-independent citrate lyase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008815; F:citrate (pro-3S)-lyase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008814; F:citrate CoA-transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 2.
DR InterPro; IPR006472; Citrate_lyase_asu.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR NCBIfam; TIGR01584; citF; 1.
DR PANTHER; PTHR40596; CITRATE LYASE ALPHA CHAIN; 1.
DR PANTHER; PTHR40596:SF1; CITRATE LYASE ALPHA CHAIN; 1.
DR Pfam; PF04223; CitF; 1.
DR PIRSF; PIRSF009451; Citrt_lyas_alpha; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR009451};
KW Lyase {ECO:0000256|PIRNR:PIRNR009451, ECO:0000313|EMBL:CZR10033.1};
KW Transferase {ECO:0000256|PIRNR:PIRNR009451}.
SQ SEQUENCE 510 AA; 54670 MW; 397174D85226FE56 CRC64;
MTVNKVGKEI PEVYAEQYGV FDGELANIKD YQEASRKIHP VKPRDKKMLN SIREAIEKTG
LKDGMTISFH HHFREGDFVI NMVMDVIAKM GIKNLSIAPS SIANVHEPLI DHIKNGVVTS
ITSSGLRDKV GAAISAGILD NPVVIRSHGG RARAIVSGDI HIDVAFLGAP SSDEYGNVNG
SHGRTACGSL GYAMVDAKYA DQVVVITDTL MPYPNTPISI PQTDVDYVVV VDAIGDPEGI
SKGATRFTKN PKELLIAEYA SKVITNSPYY KQGFSFQTGT GGASLAVSRF LKESMLEDGI
KASFALGGIT NAMVELLEEG LVEKIIDVQD FDHPSALSLG KNANHYEIDA EMYASPLSKG
SVINQLDTAI LSALEIDTDF NVNVITGSDG IIRGASGGHS DTSAACKMSL VISPLIRGRI
PTIVDTVNTV VTPGSSVDVV VTELGIAINP AREDLIEHFK SLDVPQFSIE QLKDIAYSIV
GSPDPIEYGN KVVALIEYRD GTIIDVVKNV
//
