ID A0A144P9E5_9GAMM Unreviewed; 225 AA.
AC A0A144P9E5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=tRNA (guanine(46)-N(7))-methyltransferase {ECO:0000256|ARBA:ARBA00011977};
DE EC=2.1.1.33 {ECO:0000256|ARBA:ARBA00011977};
GN ORFNames=A3K91_1397 {ECO:0000313|EMBL:AMT97001.1};
OS Psychrobacter alimentarius.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Psychrobacter.
OX NCBI_TaxID=261164 {ECO:0000313|EMBL:AMT97001.1, ECO:0000313|Proteomes:UP000076104};
RN [1] {ECO:0000313|EMBL:AMT97001.1, ECO:0000313|Proteomes:UP000076104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 27889 {ECO:0000313|EMBL:AMT97001.1,
RC ECO:0000313|Proteomes:UP000076104};
RA Lee J., Kim O.-S.;
RT "Genome sequencing of Psychrobacter alimentarius PAMC 27889.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the formation of N(7)-methylguanine at position 46
CC (m7G46) in tRNA. {ECO:0000256|ARBA:ARBA00003015}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-
CC methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:42708, Rhea:RHEA-COMP:10188, Rhea:RHEA-COMP:10189,
CC ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74269,
CC ChEBI:CHEBI:74480; EC=2.1.1.33;
CC Evidence={ECO:0000256|ARBA:ARBA00000142};
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DR EMBL; CP014945; AMT97001.1; -; Genomic_DNA.
DR RefSeq; WP_062844624.1; NZ_CP014945.1.
DR AlphaFoldDB; A0A144P9E5; -.
DR STRING; 261164.A3K91_1397; -.
DR KEGG; pali:A3K91_1397; -.
DR PATRIC; fig|261164.3.peg.1476; -.
DR OrthoDB; 9809889at2; -.
DR Proteomes; UP000076104; Chromosome.
DR GO; GO:0008176; F:tRNA (guanine(46)-N7)-methyltransferase activity; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR003358; tRNA_(Gua-N-7)_MeTrfase_Trmb.
DR PANTHER; PTHR23417; 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE; 1.
DR PANTHER; PTHR23417:SF14; PPR_LONG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02390; Methyltransf_4; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51625; SAM_MT_TRMB; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:AMT97001.1};
KW Transferase {ECO:0000313|EMBL:AMT97001.1};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
SQ SEQUENCE 225 AA; 25857 MW; 6C47E00EA8025FE7 CRC64;
MTDNIELTHG QSRAFQPEKL SPPRNFIIPN IVIENKDNLP LLLEIGAGKG KHALGFVSQN
PDKHLVAIER TRNKFDAFAK LTALQNAPNL DAIHADAIAW IVHAIAPSSV AKIFILYPNP
EQHNPNQQWL NMPFFEFLLS RLRDDGEVVL VTNIESYMDN AAQRATEIWR LPNKRYQVPI
DSQRTHFEVK YLARGETCWE LSMRKPQGYK TRFDNWQADC RGIKK
//
