ID A0A146B1P5_9BORD Unreviewed; 430 AA.
AC A0A146B1P5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=O-acetylhomoserine sulfhydrylase {ECO:0000313|EMBL:SAI69988.1};
DE EC=2.5.1.49 {ECO:0000313|EMBL:SAI69988.1};
DE EC=4.4.1.11 {ECO:0000313|EMBL:SAI69988.1};
GN Name=cysD1_2 {ECO:0000313|EMBL:SAI69988.1};
GN ORFNames=SAMEA3906487_02015 {ECO:0000313|EMBL:SAI69988.1};
OS Bordetella trematum.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=123899 {ECO:0000313|EMBL:SAI69988.1, ECO:0000313|Proteomes:UP000076825};
RN [1] {ECO:0000313|EMBL:SAI69988.1, ECO:0000313|Proteomes:UP000076825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H044680328 {ECO:0000313|EMBL:SAI69988.1,
RC ECO:0000313|Proteomes:UP000076825};
RG Pathogen Informatics;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
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DR EMBL; LT546645; SAI69988.1; -; Genomic_DNA.
DR RefSeq; WP_033535432.1; NZ_UFUJ01000001.1.
DR AlphaFoldDB; A0A146B1P5; -.
DR STRING; 123899.SAMEA3906487_02015; -.
DR GeneID; 56590710; -.
DR KEGG; btrm:SAMEA390648702015; -.
DR PATRIC; fig|123899.6.peg.2010; -.
DR eggNOG; COG2873; Bacteria.
DR OrthoDB; 9805807at2; -.
DR Proteomes; UP000076825; Chromosome 1.
DR GO; GO:0018826; F:methionine gamma-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:SAI69988.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000076825};
KW Transferase {ECO:0000313|EMBL:SAI69988.1}.
FT MOD_RES 211
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 430 AA; 46510 MW; 340616BEF6D9FCDA CRC64;
MSDSNKNWRL ETIAVHGGYR PDPTTRAVAV PIYQTVAYAF DDTQHGADLF DLKVPGNIYT
RIMNPTNDVL EQRVAALEGG IAALALASGQ AAVTYSILTL AEAGDNIVSS STLYGGTYNL
LAHTLPQYGI STRFADPSDL ASFERQIDAR TKAIFAESVG NPLGNVTDIQ ALADLAHRHG
VPLIVDNTVP SPYLLRPIEH GADIVVQSLT KYLGGHGTSL GGAIIDSGKF PWAQHKERFK
RLNEPDVSYH GVVYTEAFGA AAYIGRARVV PLRNTGAALS PFNAFQILQG IETLALRVDR
IVENAVRIAQ YLKQHPKVEW VNYAGLPEHP DHALVQKYLG GKAPGLFTFG VKGGREAGAR
FQDALNLFTR LVNIGDAKSL ATHPASTTHR QLNPEELAKA GVREETVRLS IGIEHIDDLI
ADLDQALAQV
//
