ID   A0A146JIN5_9VIRU        Unreviewed;       484 AA.
AC   A0A146JIN5;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=XRN1 5'-3' exonuclease {ECO:0000313|EMBL:BAU80239.1};
OS   Tokyovirus A1.
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Marseilleviridae; Marseillevirus.
OX   NCBI_TaxID=1826170 {ECO:0000313|EMBL:BAU80239.1, ECO:0000313|Proteomes:UP000204668};
RN   [1] {ECO:0000313|EMBL:BAU80239.1, ECO:0000313|Proteomes:UP000204668}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tokyovirus A1 {ECO:0000313|EMBL:BAU80239.1,
RC   ECO:0000313|Proteomes:UP000204668};
RA   Takemura M.;
RT   "Draft Genome Sequence of Tokyovirus, a Member of the Family
RT   Marseilleviridae Isolated from the Arakawa River of Tokyo, Japan.";
RL   Genome Announc. 4:e00429-16(2016).
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DR   EMBL; AP017398; BAU80239.1; -; Genomic_DNA.
DR   RefSeq; YP_009255110.1; NC_030230.1.
DR   GeneID; 27924739; -.
DR   KEGG; vg:27924739; -.
DR   OrthoDB; 3268at10239; -.
DR   Proteomes; UP000204668; Genome.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 1.25.40.1050; -; 1.
DR   Gene3D; 3.40.50.12390; -; 1.
DR   InterPro; IPR027073; 5_3_exoribonuclease.
DR   InterPro; IPR041412; Xrn1_helical.
DR   InterPro; IPR004859; Xrn1_N.
DR   PANTHER; PTHR12341:SF41; 5'-3' EXORIBONUCLEASE 1; 1.
DR   PANTHER; PTHR12341; 5'->3' EXORIBONUCLEASE; 1.
DR   Pfam; PF17846; XRN_M; 1.
DR   Pfam; PF03159; XRN_N; 2.
PE   4: Predicted;
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839, ECO:0000313|EMBL:BAU80239.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000204668}.
FT   DOMAIN          1..115
FT                   /note="Xrn1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03159"
FT   DOMAIN          119..210
FT                   /note="Xrn1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03159"
FT   DOMAIN          321..483
FT                   /note="Xrn1 helical"
FT                   /evidence="ECO:0000259|Pfam:PF17846"
SQ   SEQUENCE   484 AA;  56497 MW;  EB68FF9365B386F3 CRC64;
     MGVPGLFYWI QGKYPQHTRV VQKKEPTTAD NLYIDAVCFV HSSAQDVYGY NGSISFSETY
     KSFTEKQKEM EVFRLTRNAI FALTKYVKPT KRFYVLFDGV APLAKQGQQR HRRFLGSPTE
     GFDPNSITCG TEFLDRLQNY VRRGLENFCS KESFQLIFSD TSIAGEGEHK ALSFARANGP
     EESHCFYSPD GDLVILAMTL EFPKTWLLRK DHIQQWKHLL TDISGISQEF EQEIPIKDFV
     FLSCLLGNDF LPRLGMFEGK FSDTAEFLLA KYKEKGLHIF SRKTGKFLAK NTFKILKFLG
     TFEKELFDER CYFELTKQKE ERVDKTLLSA YDAKGGVDVE KYKEVFALKK QRSREQTREY
     FRGCLWVTLY YTQGCPDSGW SYKYFYPPFL SDAEQEDLVH EPFQQTVVPN QLLQLLCVLP
     PHSSHLLPRK WKKYACVYEK KELAEFYPKE VEVDLEGKFR DYESVPLIPH VDISRVQREV
     EKIR
//