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Entry: A0A147E7I0_9MICC
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ID   A0A147E7I0_9MICC        Unreviewed;       283 AA.
AC   A0A147E7I0;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   08-MAY-2019, entry version 14.
DE   SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:KTR79806.1};
DE   SubName: Full=Probable 3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:SQC30476.1};
DE            EC=1.1.1.157 {ECO:0000313|EMBL:SQC30476.1};
GN   Name=paaH {ECO:0000313|EMBL:SQC30476.1};
GN   ORFNames=AN277_0209360 {ECO:0000313|EMBL:OAX51326.1}, NCTC11038_01458
GN   {ECO:0000313|EMBL:SQC30476.1}, RSA28_07100
GN   {ECO:0000313|EMBL:KTR79806.1};
OS   Rothia kristinae.
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Rothia.
OX   NCBI_TaxID=37923 {ECO:0000313|EMBL:KTR79806.1, ECO:0000313|Proteomes:UP000073955};
RN   [1] {ECO:0000313|EMBL:KTR79806.1, ECO:0000313|Proteomes:UP000073955}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA28 {ECO:0000313|EMBL:KTR79806.1,
RC   ECO:0000313|Proteomes:UP000073955};
RX   PubMed=26793183;
RA   Midha S., Bansal K., Sharma S., Kumar N., Patil P.P., Chaudhry V.,
RA   Patil P.B.;
RT   "Genomic Resource of Rice Seed Associated Bacteria.";
RL   Front. Microbiol. 6:1551-1551(2016).
RN   [2] {ECO:0000313|Proteomes:UP000053171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RuSp02-3 {ECO:0000313|Proteomes:UP000053171};
RA   Waterworth S., Matcher G.;
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:OAX51326.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RUTW2-3 {ECO:0000313|EMBL:OAX51326.1};
RA   Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K.,
RA   Barbian K., Babar A., Rosenke K.;
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:OAX51326.1, ECO:0000313|Proteomes:UP000053171}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RuSp02-3 {ECO:0000313|Proteomes:UP000053171}, and RUTW2-3
RC   {ECO:0000313|EMBL:OAX51326.1};
RA   Waterworth S.C., Walmsley T.A., Matongo T., Davies-Coleman M.T.,
RA   Dorrington R.A.;
RT   "Identification of putative biosynthetic pathways for the production
RT   of bioactive secondary metabolites by the marine actinomycete Kocuria
RT   kristinae RUTW2-3.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [5] {ECO:0000313|EMBL:SQC30476.1, ECO:0000313|Proteomes:UP000251283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC11038 {ECO:0000313|EMBL:SQC30476.1,
RC   ECO:0000313|Proteomes:UP000251283};
RG   Pathogen Informatics;
RA   Doyle S.;
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LDRD01000063; KTR79806.1; -; Genomic_DNA.
DR   EMBL; LJBJ02000023; OAX51326.1; -; Genomic_DNA.
DR   EMBL; UASQ01000001; SQC30476.1; -; Genomic_DNA.
DR   RefSeq; WP_058743503.1; NZ_NOIV01000006.1.
DR   EnsemblBacteria; KTR79806; KTR79806; RSA28_07100.
DR   EnsemblBacteria; OAX51326; OAX51326; AN277_0209360.
DR   GeneID; 34408756; -.
DR   PATRIC; fig|37923.10.peg.333; -.
DR   OrthoDB; 862072at2; -.
DR   BioCyc; GCF_001570865:KKR01S_RS09510-MONOMER; -.
DR   Proteomes; UP000053171; Unassembled WGS sequence.
DR   Proteomes; UP000073955; Unassembled WGS sequence.
DR   Proteomes; UP000251283; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053171,
KW   ECO:0000313|Proteomes:UP000073955, ECO:0000313|Proteomes:UP000251283};
KW   Oxidoreductase {ECO:0000313|EMBL:SQC30476.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053171}.
FT   DOMAIN        6    185       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      189    283       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   SITE        142    142       Important for catalytic activity.
FT                                {ECO:0000256|PIRSR:PIRSR000105-1}.
SQ   SEQUENCE   283 AA;  31072 MW;  D46DCF4B67D37019 CRC64;
     MSGFTHVTVI GSGVLGSQIA FQAAFFGKEV MVYDISEEIL AELPTRWDRL AGFYVRDMEA
     TEDQLEQTRS RLHHSADLAQ ALAEADVVIE AVPENLELKR KVWAQIGAAA PEQAVLCTNS
     STLLPSDIAA ATGHPERFLA LHFANEVWKN NTGEVMGHAG TDPQAVQQVL EFAGQIGLVP
     IHVEKEQPGY VLNTLLVPFL NAATHLWVQD IAEPEEIDKT WRTATGSPLG PFQILDVVGM
     ETVYQINLNA GTEESKKVAQ RIKTEFIDRG RRGRDAGGGF YTY
//
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