ID A0A147END5_9MICO Unreviewed; 1051 AA.
AC A0A147END5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=NS354_07320 {ECO:0000313|EMBL:KTR85862.1};
OS Leucobacter chromiiresistens.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leucobacter.
OX NCBI_TaxID=1079994 {ECO:0000313|EMBL:KTR85862.1, ECO:0000313|Proteomes:UP000070810};
RN [1] {ECO:0000313|EMBL:KTR85862.1, ECO:0000313|Proteomes:UP000070810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NS354 {ECO:0000313|EMBL:KTR85862.1,
RC ECO:0000313|Proteomes:UP000070810};
RX PubMed=26793183;
RA Midha S., Bansal K., Sharma S., Kumar N., Patil P.P., Chaudhry V.,
RA Patil P.B.;
RT "Genomic Resource of Rice Seed Associated Bacteria.";
RL Front. Microbiol. 6:1551-1551(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DnaX/STICHEL family.
CC {ECO:0000256|ARBA:ARBA00006360}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTR85862.1}.
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DR EMBL; LDRK01000038; KTR85862.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A147END5; -.
DR PATRIC; fig|1079994.3.peg.1587; -.
DR Proteomes; UP000070810; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18137; HLD_clamp_pol_III_gamma_tau; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR022754; DNA_pol_III_gamma-3.
DR InterPro; IPR012763; DNA_pol_III_sug/sutau_N.
DR InterPro; IPR045085; HLD_clamp_pol_III_gamma_tau.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02397; dnaX_nterm; 1.
DR PANTHER; PTHR11669:SF0; PROTEIN STICHEL; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR Pfam; PF12169; DNA_pol3_gamma3; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932};
KW Reference proteome {ECO:0000313|Proteomes:UP000070810};
KW Transferase {ECO:0000256|ARBA:ARBA00022932}.
FT DOMAIN 36..180
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 385..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..1024
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1051 AA; 103027 MW; 59AA37ADA691D5DD CRC64;
MVAALYRRYR PEAFSEMIGQ SQVTDPLMTA LRTGRIGHAY LFSGPRGCGK TTSARILARC
LNCAEGPTDS PCGVCESCVE LSRDGGGSLD VVEIDAASHG GVDDARDLRE RAVFAPARDR
FKIFIIDEAH MVTPGGFNAL LKIVEEPPPH VKFVFATTEP EKVIGTIRSR THHYPFRLIA
PGTLIDYVQS LCDSEGVQVE PGVLPLVVRA GGGSVRDTLS ILDQLIAGSE TALVTAERAA
GLLGFTHAEL LDDAVAALGA HDAAAAFRAA DRVVQTGQDP RRFVEDLLER LRDLIVVNAT
TVDGAAAIFR GVPQDQLSRM FEQARAFGRG ELSRVADVVS GALDKMAGAT APRLQLELMI
ARALVHAPEA VAGADSAAPR IAAAPAGATP GAGNASADNA GPRPSAPGSA GPRPSAPGSA
GPGASTAGSA GPGASAHGPQ SQSDPLAALA AARSAAAEHT APAAPTPTVP AAPVPAAPAG
DDSNGSPASA GGQSAPNAAQ TAASIREFLT QDDAAAHAAP GGAASQSGPG AASDAQPGPP
ASRPGADHAA ASAGAPHPNE GAAKFGRPIS AVLSSAQIES IGSDAPAPPP ETPAGPVSAV
PGAAAAGAAA AGAAAGGAAA PQGGAAAPAT AAAGSPGTPS AGAVPSPDSA AAPATDAEAT
GVDGAETDAS TGGYEDLLEV WPDLLEELLE LDRDAWNAVR VVAPLALDGD VLTVGLSSES
DLAAFKSTGA GPLRETILSA VGISVKYKPK RMPAGEAAAG RGAAREPSAA ADAEEPHQAG
SAHVPTEASA TAQADTAVDA ARAAEAAPDD DPMVRAAARL SGLGPALAAP AWADPQPDAA
TSTANGGAAA PASSPEEPEQ VSSGAHPSAP HPGGAAPHAG PHAAGAPDAP APVPSGAGEP
EAAVSPSSTG ALDTAAASSG AEPGEAAPRF PDPAAFGDPY ADDPGDGPDD AGEGDPYADA
PGIAAPAGLA PTSGPAPTSG PAPTAAPHAP APNAASEPVE PATSPVSSGT PGTPATPAPP
AARPAFTRYG EAIVREVLGA RFVEERPLPQ R
//
