ID A0A147IKP9_9SPHN Unreviewed; 617 AA.
AC A0A147IKP9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Methylcrotonoyl-CoA carboxylase {ECO:0000313|EMBL:KTT95105.1};
GN ORFNames=NS355_16965 {ECO:0000313|EMBL:KTT95105.1};
OS Sphingomonas yabuuchiae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=172044 {ECO:0000313|EMBL:KTT95105.1, ECO:0000313|Proteomes:UP000073923};
RN [1] {ECO:0000313|EMBL:KTT95105.1, ECO:0000313|Proteomes:UP000073923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NS355 {ECO:0000313|EMBL:KTT95105.1,
RC ECO:0000313|Proteomes:UP000073923};
RX PubMed=26793183;
RA Midha S., Bansal K., Sharma S., Kumar N., Patil P.P., Chaudhry V.,
RA Patil P.B.;
RT "Genomic Resource of Rice Seed Associated Bacteria.";
RL Front. Microbiol. 6:1551-1551(2016).
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KTT95105.1}.
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DR EMBL; LDTF01000114; KTT95105.1; -; Genomic_DNA.
DR RefSeq; WP_058746751.1; NZ_LDTF01000114.1.
DR AlphaFoldDB; A0A147IKP9; -.
DR PATRIC; fig|172044.3.peg.308; -.
DR OrthoDB; 9763189at2; -.
DR Proteomes; UP000073923; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}.
FT DOMAIN 1..451
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 120..322
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 536..612
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 617 AA; 65165 MW; F69F1143F394712E CRC64;
MMKSLLIANR GEIACRIIRT AREMGLRTIA VYSEADAQAL HVRLADEAIL IGPAPARESY
LDAARILAAA RESGAEAIHP GYGFLSENAE FAESVIAAGL VWVGPNPDSI RAMGLKDAAK
ARMIAAGVPV TPGYLGEDQD PDRLAAEAEA VGYPVLIKAV AGGGGKGMRR VDDPAAFSEA
LASCRREAAA SFGDDRVLIE KYILSPRHIE VQVFGDRHGQ VVHLFERDCS LQRRHQKVIE
EAPAPGMDAA TREAVCGAAV RAAQAVDYVG AGTIEFIADA SEGLRADRVW FMEMNTRLQV
EHPVTEAITG VDLVEWQLRV AAGESLPIAQ GDLAIHGHAI EARLYAEDPA KGFLPAIGTL
EVFDLGDDPA IRIDTGVEEG AEITPWYDPM IAKVIAHGDT RDAAREALAD ALDEAVIWPV
RTNAGFLVQA LDHPDFASGQ VDTGLIAREG EALMPPTEPS EEALAEAAAA LIGQDGLSGF
RLNAAPRRSA RFLLDGRPIT VDFSEAGEVP LAPTDEVLIS EGGQSWSFTR WRADGLAAGG
AGDGAILSPM PGRIIAVAVT EGQAVSTGQP LVTMEAMKME HVLTAPFDGV VTDLKAETGG
QVAEGIALVR IVAEDAA
//
