ID A0A148N7Q3_9GAMM Unreviewed; 686 AA.
AC A0A148N7Q3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AXA67_09780 {ECO:0000313|EMBL:KXJ40584.1};
OS Methylothermaceae bacteria B42.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylothermaceae.
OX NCBI_TaxID=1798802 {ECO:0000313|EMBL:KXJ40584.1, ECO:0000313|Proteomes:UP000074680};
RN [1] {ECO:0000313|EMBL:KXJ40584.1, ECO:0000313|Proteomes:UP000074680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B42 {ECO:0000313|EMBL:KXJ40584.1};
RX PubMed=26779119; DOI=10.3389/fmicb.2015.01425;
RA Skennerton C.T., Ward L.M., Michel A., Metcalfe K., Valiente C., Mullin S.,
RA Chan K.Y., Gradinaru V., Orphan V.J.;
RT "Genomic Reconstruction of an Uncultured Hydrothermal Vent
RT Gammaproteobacterial Methanotroph (Family Methylothermaceae) Indicates
RT Multiple Adaptations to Oxygen Limitation.";
RL Front. Microbiol. 6:1425-1425(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXJ40584.1}.
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DR EMBL; LSNW01000030; KXJ40584.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A148N7Q3; -.
DR STRING; 1798802.AXA67_09780; -.
DR Proteomes; UP000074680; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd00158; RHOD; 1.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR11635; CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN; 1.
DR PANTHER; PTHR11635:SF152; CAMP-DEPENDENT PROTEIN KINASE TYPE II REGULATORY SUBUNIT; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 595..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..95
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 123..227
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 244..336
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT REGION 355..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 404..544
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 355..386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 76904 MW; 374EC27BCDA80AC5 CRC64;
MNLLPQDQFK QLCNGLTACE IQEGESLFER GAECNEWIYI LQGDVVLEAD GIVMDTIKGG
TDAARFPVAQ HIPRKVTARA LTQLRYIQLD YQQLNLMENY RPKASGQSRS KGDWVTKLLK
SPVFQRLPAS NLQKIVNQFE EIETESGQPI ITQGEDGDCL YIIKSGQCVI SRKPRPNAKE
IKLGELRPGD MVGEDALITG SPRSVNVTML TDGVVLKLGK EDFLELIAKP VLTKVSFETA
YREASQEALW LDVRDPDEYK RAHIKESINV PFFSLRMQLG MLQRNRRYIV VCEDGVTSAA
AAFLLLRYGF EATFLDGGMA SVPVKSLVGE GVPLEEDIGE EKDNDDVITE IPQPKDEAKE
RQRELVSHNQ EEITARVEEK SDIEEEIQSP TPPPSTQLIT EQTLEKQQQE IKKLQFERNA
LAAEKQQLQD KLKEQAELLQ KLKAQNESDK LRQELEWVRA EREKDQEKIQ SLQQQIDELE
GVIQQYFGTT DVQNVEVRVQ SLIAELHEVR DQADKDVEAM QEEVEAMRSE VERLKAELES
VKSTSDAPLQ AVDKEEPKFL SELTAVEPEQ LPLNTVVTQN AAASTNHTSK VGASILWMLV
GILLSLSIVG IVFQMESGRR LLAKFIMADS QATMYQKSSV PTQNKREKLG SEANVFEEAE
SGSALFESEG AGTDETGGEG DLFDSE
//
