ID   A0A150FN99_CLOPD        Unreviewed;       350 AA.
AC   A0A150FN99;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Arsenical-resistance protein {ECO:0000313|EMBL:KXZ39092.1};
GN   ORFNames=JWYL7_0167 {ECO:0000313|EMBL:KXZ39092.1};
OS   [Clostridium] paradoxum JW-YL-7 = DSM 7308.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae.
OX   NCBI_TaxID=1121328 {ECO:0000313|EMBL:KXZ39092.1, ECO:0000313|Proteomes:UP000092605};
RN   [1] {ECO:0000313|EMBL:KXZ39092.1, ECO:0000313|Proteomes:UP000092605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JW-YL-7 {ECO:0000313|EMBL:KXZ39092.1,
RC   ECO:0000313|Proteomes:UP000092605};
RA   Utturkar S.M., Lancaster A., Poole F.L., Adams M.W., Brown S.D.;
RT   "Draft genome sequence for Clostridium paradoxum JW-YL-7.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC       ECO:0000256|PIRNR:PIRNR005508}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|PIRNR:PIRNR005508}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC       family. {ECO:0000256|ARBA:ARBA00010110, ECO:0000256|PIRNR:PIRNR005508}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXZ39092.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LSFY01000001; KXZ39092.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A150FN99; -.
DR   STRING; 1121328.JWYL7_0167; -.
DR   PATRIC; fig|1121328.3.peg.165; -.
DR   OrthoDB; 9771457at2; -.
DR   Proteomes; UP000092605; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR004706; Arsenical-R_Acr3.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   NCBIfam; TIGR00832; acr3; 1.
DR   PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR   PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
DR   PIRSF; PIRSF005508; Acr3; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005508};
KW   Membrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|PIRNR:PIRNR005508,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR005508}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        258..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        289..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        319..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   350 AA;  38514 MW;  0CFF0BB0BA9A5314 CRC64;
     MVNETKKTAG LDFFGRYLTV WVTICIIVGV AIGQLFPQFP QTLSKFEYAK VSIPVAILIW
     LMIYPMMLKI DFTSIVEATK KPKGLTVTCV TNWLIKPFTM YLIAAFFLKI VFKGLIPSDL
     ASDYLAGAVL LGAAPCTAMV FVWSHLTKGD PAYTLVQVAV NDLILLFAFT PIVAILLGVT
     NVVVPYDTLL LSVVLFIVVP LLGGYLSRKY IIDKKGLDYF ENVFLKKFDN VTVIGLLLTL
     IIIFSFQGEV ILNNPIHIVL IAVPLIVQTF FIFFIAYGWA KVWKLPHNIA APGAMIGASN
     FFELAVAVAI SLFGLQSGAT LATVVGVLVE VPLMLALVKI ANNTRHLFEK
//