ID A0A150FUR6_CLOPD Unreviewed; 272 AA.
AC A0A150FUR6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=MscS Mechanosensitive ion channel {ECO:0000313|EMBL:KXZ40780.1};
GN ORFNames=JWYL7_1855 {ECO:0000313|EMBL:KXZ40780.1};
OS [Clostridium] paradoxum JW-YL-7 = DSM 7308.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae.
OX NCBI_TaxID=1121328 {ECO:0000313|EMBL:KXZ40780.1, ECO:0000313|Proteomes:UP000092605};
RN [1] {ECO:0000313|EMBL:KXZ40780.1, ECO:0000313|Proteomes:UP000092605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JW-YL-7 {ECO:0000313|EMBL:KXZ40780.1,
RC ECO:0000313|Proteomes:UP000092605};
RA Utturkar S.M., Lancaster A., Poole F.L., Adams M.W., Brown S.D.;
RT "Draft genome sequence for Clostridium paradoxum JW-YL-7.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXZ40780.1}.
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DR EMBL; LSFY01000001; KXZ40780.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A150FUR6; -.
DR STRING; 1121328.JWYL7_1855; -.
DR PATRIC; fig|1121328.3.peg.1868; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000092605; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR008910; MSC_TM_helix.
DR InterPro; IPR045275; MscS_archaea/bacteria_type.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30221; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR PANTHER; PTHR30221:SF1; SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF05552; MS_channel_1st_1; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..101
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 103..168
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 175..257
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 272 AA; 30919 MW; 130B2B1F8B809203 CRC64;
MQIDIIQEIN KYIVVYGMDI LTSIAVLVVG IYLSRKLRKI TRKFLEKAGI DLSLVGFISQ
LVYILGIVFV GVTVLNKLGM PTTSFVTVLG AAGFAVGLAL QGSLSNFASG VLILVFKPFR
VKDVIQTSDI LGAVEEIQIF NTILRTFDNK TIIIPNSKLT SDKIINYTLQ DKRRIDFEFG
VSYDSDIVKV KNVIREIFDK DERILKDPMP IIGVLEFADS CIKIVARPWV ITENYWPVYF
DVMEKVKYEF DKNDIVIPYP QRVIHLRNDE KI
//
