ID A0A150FZ82_GONPE Unreviewed; 938 AA.
AC A0A150FZ82;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=GPECTOR_111g256 {ECO:0000313|EMBL:KXZ42923.1};
OS Gonium pectorale (Green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Gonium.
OX NCBI_TaxID=33097 {ECO:0000313|EMBL:KXZ42923.1, ECO:0000313|Proteomes:UP000075714};
RN [1] {ECO:0000313|Proteomes:UP000075714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2863 {ECO:0000313|Proteomes:UP000075714};
RX PubMed=27102219; DOI=10.1038/ncomms11370;
RA Hanschen E.R., Marriage T.N., Ferris P.J., Hamaji T., Toyoda A.,
RA Fujiyama A., Neme R., Noguchi H., Minakuchi Y., Suzuki M.,
RA Kawai-Toyooka H., Smith D.R., Sparks H., Anderson J., Bakaric R., Luria V.,
RA Karger A., Kirschner M.W., Durand P.M., Michod R.E., Nozaki H., Olson B.J.;
RT "The Gonium pectorale genome demonstrates co-option of cell cycle
RT regulation during the evolution of multicellularity.";
RL Nat. Commun. 7:11370-11370(2016).
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|RuleBase:RU003756}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXZ42923.1}.
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DR EMBL; LSYV01000111; KXZ42923.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A150FZ82; -.
DR STRING; 33097.A0A150FZ82; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000075714; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF35; DNA MISMATCH REPAIR PROTEIN MSH2; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU003756};
KW DNA repair {ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003756};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003756}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000075714}.
FT DOMAIN 750..766
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 868..889
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 938 AA; 102511 MW; 04773F13A1DEA9BF CRC64;
MPPKPVVDDG DEEETEVAPK DLDDKSLRAF FSFFKTLTED PHIIRFFDRK GYYSIHGQAA
NLIARQFYRT TAVVRGADSG LPYVNVNRSM FETILRELLL GGTAHVVELY EQAGTGWKLA
RSATPGKLSA FDDELYRNAE MAEVPVVAAI TFTVAEGQAT VGLGYVDSAS CRLGASELLL
DDQLSGLEAV LVQLGAREVV INKDAKQLLD AGQQSRFDGL LESVGLMATE RPAALFSVKH
LEGDLAKIIK DGAVERHGDV LERRTACAAL AAVISYAEVM AEASSGNGGR YVLSLYNPGC
YMRLDATAQR ALNVLPTRQD ANTTFSLYGL LNRCRTAMGK RRLKSWLKQP LVDLAAISER
HDAVEAFVGD AELRQRLRDQ HFRGLPDVER LTRKLQSRRI KLQELHQLYR ASARLPLIEE
ALRCHEGPHA AGLVERYAEP LAQHHDAEHL QRFEELLETA LDLERLPEEY LISPSYNQEL
GALADAKAGL EEEINDLAQA AASDLNLVLD KTIKLEWHRA ANVRTRCLRI TQKEEKNVRN
KLQAKYIVIE TRKDGTKFTN RALRDAAERL NAASSQYEAM QAELVEQLVG VAATFVEVWE
AVGGVLAELD VLLSFAEAAV VAPVPYVRPE MLGADEGVIE LKECRHPNVE VQDGVNFIAN
DCVLQRGETW FQIITGPNMG GKSTYIRQVG VSVLLAQVGA FVPCASARIS VRDSIFCRVG
AGDCQMRGVS TFMAEMLETA AILRGATSHS LVIIDELGRG TSTYDGFGLA WAISEHLAGP
DVGAPTLFAT HFHELTELTA AVGVKNMQAA AVIDPATHRL TMLYSIREGA CDQSFGVHVA
ESAGFPPQVI AMANERLKQL EAGQARVRDP AAKRQRTAGG SVPATTAADR QEADIKELQA
FIQGFSKLPL DGMGPTDAVA AVDNLLRALP PRLLEAAS
//
