ID A0A150H4L4_GONPE Unreviewed; 1430 AA.
AC A0A150H4L4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184};
DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184};
GN ORFNames=GPECTOR_1g871 {ECO:0000313|EMBL:KXZ56965.1};
OS Gonium pectorale (Green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Gonium.
OX NCBI_TaxID=33097 {ECO:0000313|EMBL:KXZ56965.1, ECO:0000313|Proteomes:UP000075714};
RN [1] {ECO:0000313|Proteomes:UP000075714}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2863 {ECO:0000313|Proteomes:UP000075714};
RX PubMed=27102219; DOI=10.1038/ncomms11370;
RA Hanschen E.R., Marriage T.N., Ferris P.J., Hamaji T., Toyoda A.,
RA Fujiyama A., Neme R., Noguchi H., Minakuchi Y., Suzuki M.,
RA Kawai-Toyooka H., Smith D.R., Sparks H., Anderson J., Bakaric R., Luria V.,
RA Karger A., Kirschner M.W., Durand P.M., Michod R.E., Nozaki H., Olson B.J.;
RT "The Gonium pectorale genome demonstrates co-option of cell cycle
RT regulation during the evolution of multicellularity.";
RL Nat. Commun. 7:11370-11370(2016).
CC -!- FUNCTION: Acetyltransferase enzyme. Acetylates histones, giving a
CC specific tag for transcriptional activation.
CC {ECO:0000256|ARBA:ARBA00002581}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + L-lysyl-[protein] = CoA + H(+) + N(6)-acetyl-L-
CC lysyl-[protein]; Xref=Rhea:RHEA:45948, Rhea:RHEA-COMP:9752,
CC Rhea:RHEA-COMP:10731, ChEBI:CHEBI:15378, ChEBI:CHEBI:29969,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:61930; EC=2.3.1.48;
CC Evidence={ECO:0000256|ARBA:ARBA00000780};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXZ56965.1}.
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DR EMBL; LSYV01000002; KXZ56965.1; -; Genomic_DNA.
DR STRING; 33097.A0A150H4L4; -.
DR OrthoDB; 5490807at2759; -.
DR Proteomes; UP000075714; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15614; PHD_HAC_like; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.20.1020.10; TAZ domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031162; CBP_P300_HAT.
DR InterPro; IPR013178; Histone_AcTrfase_Rtt109/CBP.
DR InterPro; IPR035898; TAZ_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR000197; Znf_TAZ.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR13808; CBP/P300-RELATED; 1.
DR PANTHER; PTHR13808:SF1; HISTONE ACETYLTRANSFERASE; 1.
DR Pfam; PF08214; HAT_KAT11; 1.
DR Pfam; PF02135; zf-TAZ; 2.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM01250; KAT11; 1.
DR SMART; SM00551; ZnF_TAZ; 2.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF57933; TAZ domain; 2.
DR PROSITE; PS51727; CBP_P300_HAT; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50134; ZF_TAZ; 2.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000075714};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 379..462
FT /note="TAZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50134"
FT DOMAIN 772..1249
FT /note="CBP/p300-type HAT"
FT /evidence="ECO:0000259|PROSITE:PS51727"
FT DOMAIN 1251..1301
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 1312..1394
FT /note="TAZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50134"
FT REGION 470..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1074
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1430 AA; 155708 MW; 46B8C8493E3EA0B4 CRC64;
MMQSQPMQQL DASSQYPQLL GANNPAFNPS AAMPQGVMSN GAPVLIRGQR DWNGNPAQQL
LGGQGQQSMG GKLTINGMLP GQLATGSGMI PQQQPLGQSG FVPNSSANGA GMVPVGNTGM
VPNGGMLAGG GMVPNNGMMP GGGMMPNGGM VPNGGMVPNN GMIPSGGMVP NGGMVPSSGM
VPNGGMVPSS GMVPNGGMVP NGGMVPPGGM VPTGGMIPNG NMVPNGGMVP NGGMIPNGGM
VPNGGMVPNG GMVPNGGMVP NGGMVPNGGM VPNGGMVPMN PGMSMGAAGS PLLNNMGNFP
GSQHGPNGGM MGNGMPGMVP VGGGMNNPAT LPGMMPVGNS FPGPSGAGAL AQNSNMPAQM
PNAGGMLGMP GGISEDINPK VQEQYVQKQQ RWLLFLRHCA KCRAPGEDCQ LKTQCKFGKQ
LWAHILACQN SQCEYPRCSS SKELLKHHQK CQAPACPICT PVKEYVKKTR TMTQQQQQQQ
QQQQGVGQSF LPEQQGNMMP GGMMQQQQQV MRMNSGLGGQ KRPHEIMGGG VGMPGGSMEG
AGRMVPVPGM GMGDPMSGQM QQAQPVQAPV QAGLMPAQQP APKRPKNEDV LRQNTGTSLL
ETFDAKQIRV HVDLIRAAAV TQKAQQPPPP DLNDACKVCL LTKLSFEPPV LYCSSCGLKI
KRGQIFYSTP PDHGNDLKGY FCHQCFSDQK GERIAVEGVS IKKTDLVKRK NDEEIEEGWV
QCDNCEGWVH QICGMFNKGR NNNDVHYLCP DCLAVGYERG QRQRTEIRPQ AMLEAKDLPT
SKLSEWITER LNRELERERI RRAEQQGKQP YEVPPPEPLT VRMINSVMKK CEAKPKFHET
FAADGYASEF PYRQKVLLLF QSLDGVDVCL FCMYVQEYGK DCPAPNTNVV YLSYLDSVKY
FRPEIPCALG PNVSLRTFVY HQLLIAYVEY TRNMGFEQMY IWACPPMQGD DYILYCHPTK
QKTPRSDRLR NWYIDMLKLA REEGIVVHLS TLWDTYFEGG RDHRMEKCSA TYIPYMEGDY
WPGEAENQLA NITDAARGGK GPKKGAVSST GAAVPSRKAG SKGKRYGGGP ATTDEQLMSR
LGEILGGNMR EDFIVVHMQQ PCTFCRTHIH GPNIVYRYRV PPGATPPKAA PERKFEGIKL
EGGGPSVPVG TVSSLSICEA CFRDEESRAH NGGQLRLPAG VHTTDLVMER LEQHPVWERD
PDGDMDSEFF ETRQTFLSLC QGNHYQFDTL RRAKHSSMMV LYHLHNPHSP AFSSSCNLCQ
AEIEPGHGFR CTVCNDFDIC ASCKHNVGHM HPVVPHKRAL DETRQRLTEA ERRERNEALQ
RTLALLVHAC NCPNNSGCQS NSCRKVKQLF QHAMHCPVKV SGGCQLCRRT WGLLSMHAKS
CTRADCTVPR CKELKEMRRR QANRQEDKRR AAYAAMLRNQ MQQQQQPRPM
//
