ID A0A150N892_9BACI Unreviewed; 759 AA.
AC A0A150N892;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN ORFNames=B4110_2725 {ECO:0000313|EMBL:KYD32920.1};
OS Parageobacillus toebii.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Parageobacillus.
OX NCBI_TaxID=153151 {ECO:0000313|EMBL:KYD32920.1, ECO:0000313|Proteomes:UP000075324};
RN [1] {ECO:0000313|EMBL:KYD32920.1, ECO:0000313|Proteomes:UP000075324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B4110 {ECO:0000313|EMBL:KYD32920.1,
RC ECO:0000313|Proteomes:UP000075324};
RA Berendsen E.M., Wells-Bennik M.H., Krawcyk A.O., De Jong A., Holsappel S.,
RA Eijlander R.T., Kuipers O.P.;
RT "Draft Genome Sequences of Seven Thermophilic Sporeformers Isolated from
RT Foods.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYD32920.1}.
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DR EMBL; LQYW01000005; KYD32920.1; -; Genomic_DNA.
DR RefSeq; WP_062677200.1; NZ_LQYW01000005.1.
DR AlphaFoldDB; A0A150N892; -.
DR PATRIC; fig|153151.4.peg.2978; -.
DR Proteomes; UP000075324; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 502..712
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 759 AA; 87102 MW; 66C566B5588CAC26 CRC64;
MRGNIVYIAL AAVFGIIAGC GRPNISLVFI VLYAIFLFTR KRRLFLFSII TICLFYMYFV
YIDHHNKTKL SGNMTLFTIR FIAPISVDGD QLKSIVKVGK EKLQLIYYIK SAQEKQELSS
LTPKAVCTVK GRLERPALPR NPNAFDYRRY LRFHHIHWIL KPQSISLQDC HNTSPTLYEW
LLSLREKGLH TVETHFPSET VGIVQALLYG ERGQLDETLL EGYQKLGLIH LLAISGLHVT
LLVGAMFSIL IRFITKETAT IILLIFLPIY IVLTGASPSV IRASFTAMIF LVSYYWKSKL
SPLDALSITL VMMLLFDPYM LWDVGFQLSF IVTFALILSS QMILSHDSVF WRLFFTAFIA
QLSALPFLLY YFFEVSLWSI PLNIIFVPLY SFAIMPLSFA AVGTHYIHSL LSFPFIWLLQ
KIIVISSDVV AFFSSNHSLS LVLGRPSFFF LICYAAAIFA AFVQMEKRRY FSIGWVAFVI
TLHAWSPYMD RYGEVILLDV GQGDCIYIEL PYRKGVYLID TGGTLPHQRQ PWQERKRKWD
VGKDVVVPFL KSNGVRYIDK LIATHGDLDH IGAAEEIIRH FSVKQMVIGK GETKNSIQEK
LVQLAERQNI EVVKISRGDR WIEDGISFYV LHPWKTHRDD NNHSIVLYTK LGGLSWLFTG
DLEETGEREL ISVFPRLEAD VLKVAHHGSD TSTTELFLEK VQPKIALISV GKHNRYHHPS
PYVIERLRKR NVIILRTDQH GAIRYIYSKN RGTFSVMLP
//
