ID   A0A150UXK2_9PEZI        Unreviewed;       793 AA.
AC   A0A150UXK2;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
DE   Flags: Fragment;
GN   ORFNames=M433DRAFT_157239 {ECO:0000313|EMBL:KYG42998.1};
OS   Acidomyces richmondensis BFW.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Acidomyces.
OX   NCBI_TaxID=766039 {ECO:0000313|EMBL:KYG42998.1, ECO:0000313|Proteomes:UP000075602};
RN   [1] {ECO:0000313|EMBL:KYG42998.1, ECO:0000313|Proteomes:UP000075602}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BFW {ECO:0000313|EMBL:KYG42998.1,
RC   ECO:0000313|Proteomes:UP000075602};
RX   PubMed=26973616; DOI=10.3389/fmicb.2016.00238;
RA   Mosier A.C., Miller C.S., Frischkorn K.R., Ohm R.A., Li Z., LaButti K.,
RA   Lapidus A., Lipzen A., Chen C., Johnson J., Lindquist E.A., Pan C.,
RA   Hettich R.L., Grigoriev I.V., Singer S.W., Banfield J.F.;
RT   "Fungi Contribute Critical but Spatially Varying Roles in Nitrogen and
RT   Carbon Cycling in Acid Mine Drainage.";
RL   Front. Microbiol. 7:238-238(2016).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KYG42998.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JPDO01000371; KYG42998.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A150UXK2; -.
DR   STRING; 766039.A0A150UXK2; -.
DR   Proteomes; UP000075602; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000075602};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          395..666
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KYG42998.1"
SQ   SEQUENCE   793 AA;  90375 MW;  AB0DC432BAB22BA3 CRC64;
     KINGTVKGRL DINPHTGAKK LVVKNLQKST QWDSKVYSEK IWGQLDAALA IIFKDGQDVF
     SKEYLYTGVE NVCRQGGASM LFARLENKCL EHVERGIRDP LLEYAGSENV TLLKAVLAEW
     SRWKAQMVII HGIFFFLDRS YLISSSKPSL SELTPRLFRE IVFNHDILKP KIIEGACDLV
     ASDRIKQQQL DPNLFTQTVD LFHDLQVYTA SFEPAFLGMT QKYVARWSDD LIVEKSIPEY
     VELAEEFIAK EMARCEEYHL DASTRRDLLA LLEDHLVVRK ETDLVDYDAL ASMLDNQSMS
     ELTALYALLE RRRLGEKLRP AFEKWVDETG TSIVFSKDED NMVVHLLSMK RRLDLVWRIA
     FQRNESLGHG LRESFETFMN KTKKGEATWN TDNTKVGEMI AKYVDQILRG GAKAIPDVLT
     AKRASSITSV PKAVTLLNPA ETEMNNDDDE LDEDTEINAQ LDQVLDLFRF VHGKAVFEAF
     YKTHLARRLL MGRSASADAE RSMLTRLKTE CGSGFTQNLE QMFKDIELSR EELQSYKQRV
     EGRLGYEKGK SLDLSVNVLS AAAWPTYPDI PVVIPAHVKK AIDDFELHYK SKHSGRKLDW
     KHALAHCQMR ASFPLGDKEL VVSSFQAIVL LLFNGLDLDE HVPYSHILSE TGLPEAEVKR
     TLQSLACARL RPLTKHPKGK DINNTDTFTI NALFAHPKHR VKINQVQLKE TKEENKETHI
     RVAEDRNFEC QAAIVRILKS RKTISHSELV SETIKATMSR GVLAVGDIKK NIDRLIEKDY
     MEREDGGMYS YIA
//