ID A0A151AP33_9CLOT Unreviewed; 373 AA.
AC A0A151AP33;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN Name=mnaA {ECO:0000313|EMBL:KYH29386.1};
GN ORFNames=CLCOL_11340 {ECO:0000313|EMBL:KYH29386.1};
OS Clostridium colicanis DSM 13634.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121305 {ECO:0000313|EMBL:KYH29386.1, ECO:0000313|Proteomes:UP000075374};
RN [1] {ECO:0000313|EMBL:KYH29386.1, ECO:0000313|Proteomes:UP000075374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13634 {ECO:0000313|EMBL:KYH29386.1,
RC ECO:0000313|Proteomes:UP000075374};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium colicanis DSM 13634.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYH29386.1}.
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DR EMBL; LTBB01000004; KYH29386.1; -; Genomic_DNA.
DR RefSeq; WP_061858002.1; NZ_LTBB01000004.1.
DR AlphaFoldDB; A0A151AP33; -.
DR STRING; 1121305.CLCOL_11340; -.
DR PATRIC; fig|1121305.3.peg.1134; -.
DR Proteomes; UP000075374; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:UniProtKB-EC.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000075374}.
FT DOMAIN 24..366
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 373 AA; 42300 MW; B9822709AD8D77F5 CRC64;
MRKIKVMSVF GTRPEAIKMA PLVKELEKSN QIESVVCVTA QHREMLDQVL TLFDITPDYD
LNIMKEKQSL SGITTNVLRN LECILSKEQP DIVLVHGDTT TTFAASLAAF YNKIKVGHIE
AGLRTYNKYF PFPEEMNRKL TGAIADFHFA PTARNKNNLI KEGVSEDKIF ITGNTVIDAM
NYTIKENYTF DNQQLNEIDF NKRIIMVTAH RRENWGSGIE NICKALLKLK KSNEDIEIIY
LVHLNPVVKE TVYKYLEGVE GIHLLSPLDT RDTHNLMKKC YFIMTDSGGI QEEAPHLGKP
VLVLRDVTER IEAVEAGTVK VVGTNVENIV DCANILLNNE EEYYRMSKAV NPYGDGKASN
RIVEAILKHM NNM
//
