ID A0A151EC67_9EURY Unreviewed; 474 AA.
AC A0A151EC67;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KYK26214.1};
GN ORFNames=AYK26_05390 {ECO:0000313|EMBL:KYK26214.1};
OS Euryarchaeota archaeon SM23-78.
OC Archaea; Euryarchaeota.
OX NCBI_TaxID=1803821 {ECO:0000313|EMBL:KYK26214.1, ECO:0000313|Proteomes:UP000075475};
RN [1] {ECO:0000313|Proteomes:UP000075475}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK26214.1}.
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DR EMBL; LSSJ01000020; KYK26214.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151EC67; -.
DR Proteomes; UP000075475; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 11..142
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 191..416
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 474 AA; 55128 MW; 6813A6001A04492C CRC64;
MKNITLVEAA KGMSELGVYQ RHGSFDPIGL EYLGAVLDGS GYNIFILKQR KESSKEFLEK
ILSTNPDLVG FSTYSYNFQH SKNLAAMIKG TNPEVYTVFG NVHISSHPTD VDDTSIDFGI
MGEGEYVIRD LVKALDKGYD VRNLESLVYW SKGVKINPRR GRIENLDELP FPLRTEDLIK
ENKTVLMYPS TKEQKLAAIN YSRGCTFACP YCSSDNIWGK NVNWRSAKNL VDEIEYLKKK
YDINTLFFTD LTFNLNKEKI SELCDEIIDR DIEISWYSML RLEDMKGKPM INRELLERMR
RAGCNKVAFG IETFNEEILT SYNKKVSFEN TRDILDLTHQ LGIINKGYFM IGEPFLETKK
TINEIKRNLT ELPFDIIRIV YLTPFPGTSI YDRYKEKIIT KDWARYTSEE PIFSLNNLNQ
EELMEARKDI LSSFYTSENY LKTIRSKIRR FPHLREAFEE FFEFLSCEGI RVSL
//
