ID A0A151GD16_9HYPO Unreviewed; 421 AA.
AC A0A151GD16;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=VHS domain protein {ECO:0000313|EMBL:KYK54955.1};
GN ORFNames=DCS_06916 {ECO:0000313|EMBL:KYK54955.1};
OS Drechmeria coniospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Drechmeria.
OX NCBI_TaxID=98403 {ECO:0000313|EMBL:KYK54955.1, ECO:0000313|Proteomes:UP000076580};
RN [1] {ECO:0000313|EMBL:KYK54955.1, ECO:0000313|Proteomes:UP000076580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 6962 {ECO:0000313|EMBL:KYK54955.1,
RC ECO:0000313|Proteomes:UP000076580};
RX PubMed=26975455; DOI=10.1038/srep23122;
RA Zhang L., Zhou Z., Guo Q., Fokkens L., Miskei M., Pocsi I., Zhang W.,
RA Chen M., Wang L., Sun Y., Donzelli B.G., Gibson D.M., Nelson D.R.,
RA Luo J.G., Rep M., Liu H., Yang S., Wang J., Krasnoff S.B., Xu Y.,
RA Molnar I., Lin M.;
RT "Insights into Adaptations to a Near-Obligate Nematode Endoparasitic
RT Lifestyle from the Finished Genome of Drechmeria coniospora.";
RL Sci. Rep. 6:23122-23122(2016).
CC -!- SUBUNIT: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
CC {ECO:0000256|ARBA:ARBA00011446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK54955.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LAYC01000003; KYK54955.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151GD16; -.
DR STRING; 98403.A0A151GD16; -.
DR InParanoid; A0A151GD16; -.
DR OrthoDB; 922060at2759; -.
DR Proteomes; UP000076580; Chromosome 03.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR GO; GO:0016197; P:endosomal transport; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProt.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd14232; GAT_LSB5; 1.
DR CDD; cd16980; VHS_Lsb5; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR044103; GAT_LSB5.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR045007; LSB5.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47789; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR PANTHER; PTHR47789:SF1; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000076580};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 18..146
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 233..321
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 153..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..394
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 421 AA; 47328 MW; 614C7AC61957AAAD CRC64;
MFSQKKPYSA VTVTIENLTS ESFAEDDFSG IPDLVEVIKL QVSGPTEAAR AIRKKLKYGN
VHRQIRALVL LDGLIQNAGS QFQRSFADEP LLERLRVCGT SQLSDPAIRK KCTELFREWS
QYASTPGLER IARLYRELPK RKVAVTQERS KVIRETENPF GDDEEEEAER RATQRSAAAS
SSATANSDPT MMYSGQPHVK RIGSPGWGEK KDKDKSKSKA KGRGQRKPFN LEEEKEKIKS
VIAEASISST NLANALQNIN RERERISEND VAVHHFETCK QLRRRILRYI YHVESEQWLG
SLLHANDQLV HALMSFEQLD HSIDADSDSD DELAEQAHLY RMATQKSHED HVSSVTSPRA
PDVSGLSLES KKKSPPPIPK PAPFRIPPQP SRAGKAPIRP AVVRKDEDEG NDPFGDENVI
E
//
