ID A0A151GML5_9HYPO Unreviewed; 643 AA.
AC A0A151GML5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=DCS_05284 {ECO:0000313|EMBL:KYK58271.1};
OS Drechmeria coniospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Drechmeria.
OX NCBI_TaxID=98403 {ECO:0000313|EMBL:KYK58271.1, ECO:0000313|Proteomes:UP000076580};
RN [1] {ECO:0000313|EMBL:KYK58271.1, ECO:0000313|Proteomes:UP000076580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 6962 {ECO:0000313|EMBL:KYK58271.1,
RC ECO:0000313|Proteomes:UP000076580};
RX PubMed=26975455; DOI=10.1038/srep23122;
RA Zhang L., Zhou Z., Guo Q., Fokkens L., Miskei M., Pocsi I., Zhang W.,
RA Chen M., Wang L., Sun Y., Donzelli B.G., Gibson D.M., Nelson D.R.,
RA Luo J.G., Rep M., Liu H., Yang S., Wang J., Krasnoff S.B., Xu Y.,
RA Molnar I., Lin M.;
RT "Insights into Adaptations to a Near-Obligate Nematode Endoparasitic
RT Lifestyle from the Finished Genome of Drechmeria coniospora.";
RL Sci. Rep. 6:23122-23122(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK58271.1}.
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DR EMBL; LAYC01000002; KYK58271.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151GML5; -.
DR InParanoid; A0A151GML5; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000076580; Chromosome 02.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd18044; DEXXQc_SMUBP2; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 2.40.30.270; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR048761; SMUBP-2_HCS1_1B.
DR PANTHER; PTHR43788:SF19; DNA-BINDING PROTEIN SMUBP-2; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF21138; SMUBP-2_HCS1_1B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000313|EMBL:KYK58271.1};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000076580}.
FT DOMAIN 17..140
FT /note="Helicase SMUBP-2/HCS1 1B"
FT /evidence="ECO:0000259|Pfam:PF21138"
FT DOMAIN 212..413
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 435..628
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 505..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..539
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 643 AA; 70548 MW; 58CC85D76C7261F6 CRC64;
MPSTREPLDI PSFAGTQLAL LTNELQTEID ETSALVSSHA PVALQRAGLA ITNLVLSSQR
TGFGGRTVVE LTSDSATSSL GCLPEHGIRT GDIVLVTEQP AGSAKKREIR ELEGKGARGV
VVKVQRETVS VALDEGKDED ARLNGRVWIV KLADEVTYRR MNRTMEKLQT MGDGEYTSLI
RVLFGLSSPS PVGKDLSKDE QVGKLEWLDP SLNESQKDAV RFALASREVA LIHGPPGLVK
RKQRVLVCGP SNVSVDNIVE RLSPHKVPIV RLGHPARLLP SVVNHSLDVL THTSEAGAIV
QDVRAEMDAK QASIKKTKSG KERRSIYADL KELRKEYRER ERRCVSNLVG GSKVVLATLH
GAGGFQLQRE KFDVVIIDEA SQALEAQCWV PLLSATKVVC AGDHLQLPPT VKSINSKVKP
PQAKDGTKPV KGMTLETTLF DRLLALHGSS IKRMLTTQYR MHDKIMRFPS DELYHSLLVA
ADSVKSRLLK DLEYEVEDNE DTGEPVIFID TQGGDFPEKN DEDDKDNVKK GKAALHGDSK
SNDMEAALVR QHIERLVKAG VRPDDIAVVT PYNAQLALLA PLKAQYPGME LGSVDGFQGR
EKEAVIVSLV RSNPDGEVGF LAEKRRLNGE DSTSKRWQEM AKC
//
