ID A0A151GNL7_9HYPO Unreviewed; 664 AA.
AC A0A151GNL7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Lysophospholipase {ECO:0000256|ARBA:ARBA00013274, ECO:0000256|RuleBase:RU362103};
DE EC=3.1.1.5 {ECO:0000256|ARBA:ARBA00013274, ECO:0000256|RuleBase:RU362103};
GN ORFNames=DCS_05648 {ECO:0000313|EMBL:KYK58631.1};
OS Drechmeria coniospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Drechmeria.
OX NCBI_TaxID=98403 {ECO:0000313|EMBL:KYK58631.1, ECO:0000313|Proteomes:UP000076580};
RN [1] {ECO:0000313|EMBL:KYK58631.1, ECO:0000313|Proteomes:UP000076580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 6962 {ECO:0000313|EMBL:KYK58631.1,
RC ECO:0000313|Proteomes:UP000076580};
RX PubMed=26975455; DOI=10.1038/srep23122;
RA Zhang L., Zhou Z., Guo Q., Fokkens L., Miskei M., Pocsi I., Zhang W.,
RA Chen M., Wang L., Sun Y., Donzelli B.G., Gibson D.M., Nelson D.R.,
RA Luo J.G., Rep M., Liu H., Yang S., Wang J., Krasnoff S.B., Xu Y.,
RA Molnar I., Lin M.;
RT "Insights into Adaptations to a Near-Obligate Nematode Endoparasitic
RT Lifestyle from the Finished Genome of Drechmeria coniospora.";
RL Sci. Rep. 6:23122-23122(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid +
CC H(+) + sn-glycerol 3-phosphocholine; Xref=Rhea:RHEA:15177,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16870,
CC ChEBI:CHEBI:28868, ChEBI:CHEBI:58168; EC=3.1.1.5;
CC Evidence={ECO:0000256|RuleBase:RU362103};
CC -!- SIMILARITY: Belongs to the lysophospholipase family.
CC {ECO:0000256|ARBA:ARBA00008780, ECO:0000256|RuleBase:RU362103}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK58631.1}.
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DR EMBL; LAYC01000002; KYK58631.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151GNL7; -.
DR STRING; 98403.A0A151GNL7; -.
DR InParanoid; A0A151GNL7; -.
DR OrthoDB; 1826981at2759; -.
DR Proteomes; UP000076580; Chromosome 02.
DR GO; GO:0004622; F:lysophospholipase activity; IEA:UniProtKB-EC.
DR GO; GO:0102545; F:phosphatidyl phospholipase B activity; IEA:UniProtKB-EC.
DR GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002642; LysoPLipase_cat_dom.
DR PANTHER; PTHR10728; CYTOSOLIC PHOSPHOLIPASE A2; 1.
DR PANTHER; PTHR10728:SF62; LYSOPHOSPHOLIPASE; 1.
DR Pfam; PF01735; PLA2_B; 2.
DR SMART; SM00022; PLAc; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51210; PLA2C; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00555,
KW ECO:0000256|RuleBase:RU362103};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963, ECO:0000256|PROSITE-
KW ProRule:PRU00555};
KW Lipid metabolism {ECO:0000256|PROSITE-ProRule:PRU00555,
KW ECO:0000256|RuleBase:RU362103};
KW Reference proteome {ECO:0000313|Proteomes:UP000076580};
KW Signal {ECO:0000256|RuleBase:RU362103}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|RuleBase:RU362103"
FT CHAIN 26..664
FT /note="Lysophospholipase"
FT /evidence="ECO:0000256|RuleBase:RU362103"
FT /id="PRO_5007358737"
FT DOMAIN 49..622
FT /note="PLA2c"
FT /evidence="ECO:0000259|PROSITE:PS51210"
SQ SEQUENCE 664 AA; 70300 MW; 8C9F10CA5C613CCB CRC64;
MLAPRPMILL AALLPSLALL VPVQAHVVEQ RADNDDDSAA ASYAPSSVAC PSPVPTIRHA
TNLSAEETAW LPVRDRNIVS ALKTLLGRVN IGDIDVNAYI DNIVKDVDAD VAEASLPRIG
IAVSGGGYRA LMNGAGALAA FDDRTTHSSG QGQLAGLLQA STYLSGLSGG SWLVGSLFVQ
NFTTVQSIVS STSGFLSTLW QFGDSILEGS PPPLSHGSRR PACPLLTSFA RSLGPKGLRT
GQYYRALRDS VQAKTDAGFN TTITDYWGRA LSYQLVNPTD GGPAFTFSSI ANSSDFSQAQ
TPMPLIVAIE RAPGQLQIAP NSTIFEFNPW EMGSYDTGAS FFAPLQYVGS NFSDGVVGGG
GKKCVTGVDN AGFVMGTSSS LFNQAFLQLG KVSAGPDFLL NALNESLGNI GEENRDIASW
PNPFYKLSAG SNINANASLL TLVDGGEALE NIPLHPLTLK ARRVDVIFAI DGSADTNTSW
PNGTALVATY ARSNGNDPPA NNTLFPPVPD QNTFVNLGLN RRPTFFGCDN SSTPLVVYIP
NTPYTFLSNV STFDLSYTDT ERDQIVQNGY NVATMANATV DANWPACVGC AILARSFGRT
KTKVPAKCVD CFSRYCWNGT TNSTQPTLYE PQLVVTSGSA RRVQAVAAAA LMLSTFAMLF
LGLA
//
