ID A0A151GRW8_9HYPO Unreviewed; 1050 AA.
AC A0A151GRW8;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 13-SEP-2023, entry version 26.
DE RecName: Full=Cytoskeleton assembly control protein Sla2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DCS_00886 {ECO:0000313|EMBL:KYK59752.1};
OS Drechmeria coniospora.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Drechmeria.
OX NCBI_TaxID=98403 {ECO:0000313|EMBL:KYK59752.1, ECO:0000313|Proteomes:UP000076580};
RN [1] {ECO:0000313|EMBL:KYK59752.1, ECO:0000313|Proteomes:UP000076580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 6962 {ECO:0000313|EMBL:KYK59752.1,
RC ECO:0000313|Proteomes:UP000076580};
RX PubMed=26975455; DOI=10.1038/srep23122;
RA Zhang L., Zhou Z., Guo Q., Fokkens L., Miskei M., Pocsi I., Zhang W.,
RA Chen M., Wang L., Sun Y., Donzelli B.G., Gibson D.M., Nelson D.R.,
RA Luo J.G., Rep M., Liu H., Yang S., Wang J., Krasnoff S.B., Xu Y.,
RA Molnar I., Lin M.;
RT "Insights into Adaptations to a Near-Obligate Nematode Endoparasitic
RT Lifestyle from the Finished Genome of Drechmeria coniospora.";
RL Sci. Rep. 6:23122-23122(2016).
CC -!- SIMILARITY: Belongs to the SLA2 family.
CC {ECO:0000256|ARBA:ARBA00010135}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK59752.1}.
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DR EMBL; LAYC01000001; KYK59752.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151GRW8; -.
DR STRING; 98403.A0A151GRW8; -.
DR InParanoid; A0A151GRW8; -.
DR OrthoDB; 7775at2759; -.
DR Proteomes; UP000076580; Chromosome 01.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd17007; ANTH_N_Sla2p; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR035964; I/LWEQ_dom_sf.
DR InterPro; IPR002558; ILWEQ_dom.
DR InterPro; IPR030224; Sla2_fam.
DR PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR10407:SF15; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR Pfam; PF07651; ANTH; 1.
DR Pfam; PF01608; I_LWEQ; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00307; ILWEQ; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF109885; I/LWEQ domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50945; I_LWEQ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000076580}.
FT DOMAIN 7..136
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT DOMAIN 808..1050
FT /note="I/LWEQ"
FT /evidence="ECO:0000259|PROSITE:PS50945"
FT REGION 266..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 309..618
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1009..1036
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 287..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1050 AA; 118569 MW; 94105508AEE5D9BF CRC64;
MASMRSEHAK TDQELAISIK KATNTDEISP KRKHVRACIV YTWDHRSAHA FWSGIKVQPI
LADEVQTFKA LITIHKVLQE GHPSALKEAM ANRSWIDGLN RGMAGDGLRG YGPLIREYVF
YLLAKLSFHQ QHIEFNGTFE YEEYLSLKAI NDPNEGYETI TDLMILQDKI EQFQKLIFSH
FRNVGNNECR ISALVPLVQE SYGIYKFITS MMRAMHSITG DDEALQPLRQ RYDAQHYRLI
KFYYECSNLR YLTSLITIPK LPQDPPNLLT EGGDAPALPS RPKQEIERQI TPPKEPKSEE
PGEISEFWKS ELDRQNRDYE EQQRVLEERQ AAALLAQQQA QMQAQRDFEE QQRRLAEQQK
RDQEALLAQQ SQWQTQGRLA ELEQENFNAR AQYERDQLML QQYDQRVKAL EGELGQIQNS
LGQQITSKDD QIRALQEQVN TWRTKYESLA KLYSQLRHEH LDLLQKFKTV QLKASSAQEA
IDKREKLERE IKTKNLELAD MIRERDRALH DKDRVHGSNK DEVERLKREL RMAQDKADNL
ERSKGNELST MLAKYNREMS DLEEALRNKS KALEEAQSSL RDGSSDLEKL LRDKEYELEV
YKTGMDETLL KLNELEQNQN DSGHALDGQI DALILSNLDK LNDVIDSVLQ AGVSRVDDAL
YELDSSMQAG NQNASPTYVL SQIEKASASA MEFATSFNNF IADGPNSTHG DLIKAINVFS
GAIADVCSNT KGLTRLATDE KKTDGLMNGA RQSAQSTLQF FRGLQSFRLE GMEPLQKTDV
VINNNNDVQI NLQKLNKLVE AFAPGFGKLA NNKGDLGDLV DSELSKAADA IAAAAARLAK
LRNKPRDGYS TYEVKVHDSI LDAATAITNA IGQLIKAASA TQQEIVQAGR GSSSRTAFYK
KNNRWTEGLI SAAKAVASST NTLIETADGV LSRRNSPEQL IVASNDVAAS TAQLVAASRV
KAGFMSKSQE KLEQASKAVG AACRALVRQV QSLIKERSQD EDAVDYTKLG AHEFKVREME
QQVEILQLEN ALSSARHRLG EMRKISYQEE
//
