ID A0A151HXM5_9HYME Unreviewed; 1129 AA.
AC A0A151HXM5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Histone-lysine N-methyltransferase eggless {ECO:0000313|EMBL:KYM75315.1};
GN ORFNames=ALC53_14286 {ECO:0000313|EMBL:KYM75315.1};
OS Atta colombica.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=520822 {ECO:0000313|EMBL:KYM75315.1, ECO:0000313|Proteomes:UP000078540};
RN [1] {ECO:0000313|EMBL:KYM75315.1, ECO:0000313|Proteomes:UP000078540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Treedump-2 {ECO:0000313|EMBL:KYM75315.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYM75315.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Atta colombica WGS genome.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KQ976748; KYM75315.1; -; Genomic_DNA.
DR RefSeq; XP_018058434.1; XM_018202945.1.
DR RefSeq; XP_018058435.1; XM_018202946.1.
DR RefSeq; XP_018058436.1; XM_018202947.1.
DR AlphaFoldDB; A0A151HXM5; -.
DR STRING; 520822.A0A151HXM5; -.
DR GeneID; 108693800; -.
DR OrthoDB; 2877903at2759; -.
DR Proteomes; UP000078540; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0140938; F:histone H3 methyltransferase activity; IEA:UniProt.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd01395; HMT_MBD; 1.
DR CDD; cd10517; SET_SETDB1; 1.
DR CDD; cd21181; Tudor_SETDB1_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 2.170.270.10; SET domain; 2.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR007728; Pre-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR047232; SETDB1/2-like_MBD.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR041292; Tudor_4.
DR InterPro; IPR041291; TUDOR_5.
DR PANTHER; PTHR46024; HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS; 1.
DR PANTHER; PTHR46024:SF1; HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS; 1.
DR Pfam; PF01429; MBD; 1.
DR Pfam; PF05033; Pre-SET; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF18358; Tudor_4; 1.
DR Pfam; PF18359; Tudor_5; 1.
DR SMART; SM00391; MBD; 1.
DR SMART; SM00468; PreSET; 1.
DR SMART; SM00317; SET; 1.
DR SMART; SM00333; TUDOR; 2.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50982; MBD; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50867; PRE_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Methyltransferase {ECO:0000313|EMBL:KYM75315.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000078540};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KYM75315.1}.
FT DOMAIN 615..684
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT DOMAIN 744..816
FT /note="Pre-SET"
FT /evidence="ECO:0000259|PROSITE:PS50867"
FT DOMAIN 819..1104
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 1113..1129
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 488..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..1023
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 898..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 962..983
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1019
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1129 AA; 129103 MW; E54733F078DB6F8E CRC64;
MAQAQSAEII ELMSDEDEKK TRKTKSKGYN SNCVNFKCCS GINMKVAPSF ACAFYGVSLE
KKKKRIICKE CFNAALQHQK QLVQAFVENR SLLDCYFPDH TMEVEISDSD DSDDEKKKEL
EKDNNEYIPE DVLLDIKDKL NDTLSHIYKK YNVEQHAKVA CETLKQRWRD ICAANDSLNT
EIREIMRTVD KLRNNLYEDF RPQIKMLEEL QINDEITETA HPLVATKKVT QVRVPPSSLL
QDNQLEVLAI EPSCTKEIII PNLPPTGPLL KHSPEVDDIV YVMKSPVMPW IKAKVLNIVS
NPWNIRVRLI QKKYNAAIKT VSGKLLATTE LSKVMIPVGT RVVAIFHDVV SNNYYSGIIA
ETPKSINKYR YLVFFDDGYA QYVVHNDILL VWETSSRIWE DIPSESREFV KKYLESYPER
PMVKLQPGQI VKTEWNGKWW LARVVQVDAS LVQMHFDADK RTEWIYRGST RLGPLFLEVR
KANARQQLQQ SGNVHTRHRI PAPSNKNNLP YVEYTSNVEE DVTQHLQAEK ATVATNVASI
TPSTALQQPR AVAKKSTAKR QNNIDTTTYN STVETKPSHS IVFYHTQRKY EPKKYVAHKC
GPRCIKGIKV SHDDLKGLSP LSIPLLCGWH RQLCKFSKGK KVILYQTPCG VRLRNMEELH
RYLRITNSTL SVDLFDFDYW VRAFADFVVE KCFINIKDLS YGVENVPIPC VNDLDHTQPD
TIRYTTRREP TEGVYLNLDP AFLCSCDCED DCQDKEKCQC WQLTIQGATL GGKMPNSAVG
YIYKRLPEPV TTGIYECNSG CKCSVKTCLN RVVQHPLRLK LQVFKTGPRG WGIRCLNDIP
HGAFICIYAG RLLTEQGANE GGKNYGDEYL AELDYVEVVE GFKEGYESDV LEPEILMSST
EDDNKKKADV SDEEEDNTKE STNDSDEDFN IDSYVASCNN DLLETTAESS SIRKRLRKRK
RHEIDNQPDV SEENSDDESI TRGLENTAKS STNEHQDMIN ISDDDDSRND VRREPSRFEP
NLEPNQIERL TFKSVRDYFG EDEAVYIMDA KTTGNIGRYL NHSCDPNVFV QNVFVDTHDV
RFPWVAFFAL QYIKAGQELT WNYSYDVGSI PGKVIICKCG AANCRGRLL
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