ID A0A151I365_9HYME Unreviewed; 1705 AA.
AC A0A151I365;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Low-density lipoprotein receptor-related protein 6 {ECO:0000313|EMBL:KYM82832.1};
GN ORFNames=ALC53_06745 {ECO:0000313|EMBL:KYM82832.1};
OS Atta colombica.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=520822 {ECO:0000313|EMBL:KYM82832.1, ECO:0000313|Proteomes:UP000078540};
RN [1] {ECO:0000313|EMBL:KYM82832.1, ECO:0000313|Proteomes:UP000078540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Treedump-2 {ECO:0000313|EMBL:KYM82832.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYM82832.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Atta colombica WGS genome.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; KQ976507; KYM82832.1; -; Genomic_DNA.
DR STRING; 520822.A0A151I365; -.
DR Proteomes; UP000078540; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 3.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 4.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR46513:SF36; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN; 1.
DR PANTHER; PTHR46513; VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF00057; Ldl_recept_a; 3.
DR Pfam; PF00058; Ldl_recept_b; 11.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00192; LDLa; 3.
DR SMART; SM00135; LY; 20.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR SUPFAM; SSF63825; YWTD domain; 4.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 3.
DR PROSITE; PS51120; LDLRB; 12.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000313|EMBL:KYM82832.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KYM82832.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000078540};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1481..1502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 136..181
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 182..224
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 225..270
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 271..313
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 449..491
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 492..534
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 535..579
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 580..622
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 693..708
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
FT REPEAT 755..797
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 798..840
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 841..883
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1157..1199
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1572..1705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1572..1624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1369..1384
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1405..1420
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 1705 AA; 191777 MW; 9A478255A9DE707C CRC64;
MNTCSSTKFH LRPVNEARND ENDEQDSQGR RRSSPRVICS YRAAIAPRLL RFHLIWIAAD
VDNLFVLKSL IAEQTRLMRS AMTLVNRFCL NPRSPLLLFG THKDIRVTNI SRSNKVNIII
KDLSEGASLD FFYERELICW SDSSLEMIQC IRYNGTHTGE KITVVNSSLI SPDGLACDWF
TDKLYWTDGE KNRIEVTSID GRNRKVLFWN DIYQPRAIAL APMEGYLFWT DWGDVPKIER
ASMDGDPNTR EIIVSDDIFW PNGLTIDYEN RLVYWADGRL HFIAVMDYHG GNRRRLINRD
LDYPFAITFF DNRLYWTDWK TWCIHSYDIN QLQSHPRELF HGEYIPGDIE VWDARRQPSG
NNPCKRNNGN CSHLCLLSSK EPGYSCACPT GVKLIDKHTC ANRPEQLLLI VQRTEICRIS
LDSPDYTNFV LPLTGIKHAI AIDFDPVEEL LYWTDEQTTA IRRAPLDGMS QQNVISTEVA
NPDGIAIDWI ARNLYWTDTG TDRIEVARLD GKYRRVLVNE DLFEPRAIAL APEHGWMFWT
DWSEKRPKIE RSNLDGSERT LLITKDIVWP NGIALDLERN KIYWCDAKTD KIEVSNMDGT
DRREVITDNL PHLFGLTLLG DYLYWTDWQR RSIDRAHKLT GGEREVIVDQ VPNVMGIKAI
HLGKMNASNS PCARDNGGCS HLCFNRPNNR YVCACQMGYE LTKDKRTCVV PEAFLLFSRR
ENLGRISIEN INNDNIIPVT GIKDASAIDF DLSENRIYWT DVKLKTITRV FINGSDIEKI
VDLGLESPEG IAFDWIAHNL YWSDTITRRI EMIRIEGGSR KILLWQNLLE PKNVAVDPER
GHLYWAEWGN TGSIERAFLD GTQRQVIVSH IGRANGLTID HVGRKLYWAD ISTPAINCYD
LLTQRGDVII SRHIVYPFSV TQYRDFIYWA DWNTGDIERA DKITGANRTK IHTNLASVTD
LKVFHASRQS GSNPCAIANG NCSHLCIALP DSNEGASVIH KCACPTHYNL ARDNRTCMAP
RHFMIYSQRT AIVRYLPDQT DDCADVTLRV QGLKNVRAIE FDPVTQHVYW IDGRVTIRRA
LENQTQQQQH SSTVVVSIGN GHLFDLALDP LGRLLFWTCS TNDALNVTRL DNGSALGIVV
KGDGEKPRHI AIYSQQRLLF WTDIGKKRVV RSKMDGKERH VIASDLLEQP TGLTVDTMTY
VVYWAYSKHI ECSNFEGSDR KLLTSTQGSA LHLAVLFNYL YWYDRDAQVI ERVNKTFDGN
TRRGTQVTTG RTSFTDLIAI NMPEDLLMET HVCSPFNDYG GCSHFCVGTN TIADEATATL
PRCSCPKSLV LSDDGRTCRA APVCGNDHFT CAAPNAAVSK DCIPATWKCD GQTDCSDGSD
ELGCPTCSRD QFRCQNHCIE LSLVCDGTQQ CPDGSDEAQC CEIGQFQCVG NGVCISGTSL
CDGWDDCADG SDEVPPACMS PHNPHRQNAG PGINESGKTT YIIIILAVVF VVGTSILSYY
YCRKKFTGNE GLPDILHDSA GDPLSPKPSN NRMVKPMFVS QKNNRKDGGG SGGIKIGMEA
VRMSMLNGSS LGSSYDRSHI TGASSSTRGS SAGGYPQETL NPPPSPATIV SSTRCSSSNA
SRYKPYRHYR SINQPPPPTP CSTDVCDESD SNYPARYRYE SEPFPPPPTP RSVYHSDAAI
SCPPSPSSRS STYFSPLPPP PSPVP
//
