ID A0A151I759_9HYME Unreviewed; 378 AA.
AC A0A151I759;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cysteine-rich with EGF-like domain protein 2 {ECO:0000313|EMBL:KYM93920.1};
GN ORFNames=ALC62_15455 {ECO:0000313|EMBL:KYM93920.1};
OS Cyphomyrmex costatus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Cyphomyrmex.
OX NCBI_TaxID=456900 {ECO:0000313|EMBL:KYM93920.1, ECO:0000313|Proteomes:UP000078542};
RN [1] {ECO:0000313|EMBL:KYM93920.1, ECO:0000313|Proteomes:UP000078542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS0001 {ECO:0000313|EMBL:KYM93920.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYM93920.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Cyphomyrmex costatus WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CRELD family.
CC {ECO:0000256|ARBA:ARBA00005897}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KQ978451; KYM93920.1; -; Genomic_DNA.
DR RefSeq; XP_018405320.1; XM_018549818.1.
DR AlphaFoldDB; A0A151I759; -.
DR STRING; 456900.A0A151I759; -.
DR GeneID; 108781743; -.
DR OrthoDB; 337149at2759; -.
DR Proteomes; UP000078542; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00064; FU; 1.
DR InterPro; IPR021852; DUF3456.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR24038:SF12; INTEGRIN BETA-LIKE PROTEIN E; 1.
DR PANTHER; PTHR24038; STABILIN; 1.
DR Pfam; PF11938; DUF3456; 2.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00261; FU; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000078542};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..378
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007582003"
FT TRANSMEM 318..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 151..193
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 183..192
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 378 AA; 41934 MW; F94DC20D59BE0F89 CRC64;
MRVPTSIVFL SIFVILSTCM SSIQCEKGKL DQEDLKSQKF PSCAACKLLI NSFKKGFEKT
SRGKFEGGDS AWEEDKLGSY SRSEIRLIEI QENLCKDVER GQVQCQSLAE ELESQIEEWW
FKHQDTHPDI HDYICIEKTE RCCPKDHYGP NCTQCPGYPD NICNNNGKCK GAGTRKGSGD
CFCEKGYLGD ICSECAPGYY ESYKDKKTLL CSACHAACDG PCRGAGPKDC AKCAAGWYMI
ESKGCFDIDE CLKNDICPGN QFCVNKEGSY VCLACDKACN GCTGDGPDMC IKCTENYHKE
DNLCTNSDFL GRKKQENLAR YLTYFGLCVA TCIIFQRNVY VASVIGLLVA VYISVSEYMI
AHSNVQDTTA NMDILGSA
//
