ID A0A151I8Q0_9HYME Unreviewed; 791 AA.
AC A0A151I8Q0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=ALC62_14345 {ECO:0000313|EMBL:KYM95015.1};
OS Cyphomyrmex costatus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Cyphomyrmex.
OX NCBI_TaxID=456900 {ECO:0000313|EMBL:KYM95015.1, ECO:0000313|Proteomes:UP000078542};
RN [1] {ECO:0000313|EMBL:KYM95015.1, ECO:0000313|Proteomes:UP000078542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS0001 {ECO:0000313|EMBL:KYM95015.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYM95015.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Cyphomyrmex costatus WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR EMBL; KQ978339; KYM95015.1; -; Genomic_DNA.
DR RefSeq; XP_018404133.1; XM_018548631.1.
DR AlphaFoldDB; A0A151I8Q0; -.
DR STRING; 456900.A0A151I8Q0; -.
DR GeneID; 108780815; -.
DR OrthoDB; 2943236at2759; -.
DR Proteomes; UP000078542; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20338; BRcat_RBR_RNF19; 1.
DR CDD; cd20355; Rcat_RBR_RNF19; 1.
DR CDD; cd16629; RING-HC_RBR_RNF19; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 2.20.25.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR11685:SF427; RBR-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000078542};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 336..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 107..326
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 111..159
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 586..620
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..705
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 706..720
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 791 AA; 85528 MW; 7CB56994D875F46D CRC64;
MFKENENGVG GCNGAPPRPR RLFPRFSLRR LLHSSPLIGR RIARTPSASN RNAKAKDHAN
SRATDVEKGE ARVSNGSSHF QFHNIDLQRA PSKGSVLSSA GKSNENGLMD CPLCLAELPV
EFFPIIQSCH HRSCYDCFQQ YLKMEISESR VNIACPECSE PLHPNDIRMI LNDQTQLEKY
EDFMVRRVLA IEPDARWCPA PDCSFAVIAS GCASCPKLRC ERPGCDSYFC YHCKARWHPN
QTCDAARAQR SQYYERSSSL SFSQTDSQHR DDIKPCPRCQ VLIVKMDDGS CNHMTCAVCG
AEFCWLCMKE ISDLHYLSPS GCTFWGKKPW SRKKKILWQL GTLVGAPIGI GLVASIAFPA
MIIGIPVWVG QKLYTRYEKA NKHKRNAFIA GGVTASVLVS PVLAGLAVGI GVPILLFYVY
GVVPVSLCRS GGCGVSTSGT GVRFEFDDEN ELMGALGVRN GGDAASIDVA SHRGGNPSIG
EASLSLGSGS QLEKLGREND RESASNVALA GTSLAGSIAS SVLPGGQRLE VQADVTSTQR
FSLCSETASA ATSLSEKSVN ASIALDDGAA STRALAGSVL NFKMDGSSIS GGRSTEGEQA
ASSANDGHMD SAGQATSLSS LEEVAPGLAK RIRRKLTFDR QCSDSSSWTM CGEDGGSERV
RFDDHVSVIE ADQERIVGKL EGCVVNNRSA GGRKRNKDSE IEMEVQKTSK NSNGELNAES
PVDDTSRERV NVATLKNVFF HASAVSTDRE KRLSVIEEPM PIVPHISGNQ IFTPLHNECQ
SPTSTDKSLQ C
//
