ID   A0A151IA89_9HYME        Unreviewed;       796 AA.
AC   A0A151IA89;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN   ORFNames=ALC62_13120 {ECO:0000313|EMBL:KYM96225.1};
OS   Cyphomyrmex costatus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Cyphomyrmex.
OX   NCBI_TaxID=456900 {ECO:0000313|EMBL:KYM96225.1, ECO:0000313|Proteomes:UP000078542};
RN   [1] {ECO:0000313|EMBL:KYM96225.1, ECO:0000313|Proteomes:UP000078542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MS0001 {ECO:0000313|EMBL:KYM96225.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYM96225.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Cyphomyrmex costatus WGS genome.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
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DR   EMBL; KQ978228; KYM96225.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A151IA89; -.
DR   STRING; 456900.A0A151IA89; -.
DR   Proteomes; UP000078542; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   CDD; cd02257; Peptidase_C19; 1.
DR   CDD; cd18809; SF1_C_RecD; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR049163; Pif1-like_2B_dom.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR47642; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR47642:SF6; ATP-DEPENDENT DNA HELICASE; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   Pfam; PF21530; Pif1_2B_dom; 1.
DR   Pfam; PF00443; UCH; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS50235; USP_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044, ECO:0000313|EMBL:KYM96225.1};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078542}.
FT   DOMAIN          525..791
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
SQ   SEQUENCE   796 AA;  90572 MW;  73AAC0F6697730D4 CRC64;
     MISKLNADQR RVFNGVTDAI SSDKEILRLY VSGEGGTGKS FLIQTIKCWI KQNLNKDTAI
     TAPTGMAAFN VNGLTAHRLF QLPVEHGRTP KYKPLADHVL KILRTDLKDV SLIVIDEVSM
     ISNIFFMYIN LRLCEIYNTT DCDDGWFGRK HVLLFGDLLQ LPPVLEDPAF IHLTEEKVRK
     YLGSLSATNL WTNLFDYDEL TINMRQQGDG SYRELLSRIR VGLLIPSDCD ILEKRKISFK
     GEFFETRLNE LCDFINNFTS IVCLLPNNHM CDQLNAAMLN RITSKEIFLI AEDTIDCISY
     MKKKVEKVLS NNDDDDTKTA GLSRRIRIKI GAKVMIRRNI DASLGLVNGT IATVVSVSQD
     KTTDYIEKIK VRLPSGLEYF IERVSVKFPV MDRVYVTRKQ FPLSLSYGIT IHKSQGLSLQ
     NAVMDLGNNV FSCGQVYVAL SRVTSLDGLH LINFDPSSVF ASEMAIIEYN RLKRIGKLES
     EIIAVSKQRY RKVKDVSWTL SKLITSVQES GQKEAPIKKT AWIIRGFQNI DKVSCYANAT
     LQCLLNLYTF RKELLNYDKL DVLNLFAHQY EHGTSNLNTY DIRQSLGEYF STVIKRNALE
     FITALCTKYD YINNMVEHKV ICNYRCNSCG NTKVITNNNV ILSLSINNLK KKSYNLDDLL
     KTTFSSSWCQ TFDKLCERCG RNDVLFKSEL VPPKEILIIN ITSFSSEDGK SEKIPHKFSL
     CAVPTTKLII PGQTYKVMSA IFHYGSCIDE GHYTSMCKKG TSWIEIDDAQ VIKRQWPRGA
     KDISILFLQK NISKNI
//