ID A0A151IE93_9HYME Unreviewed; 2430 AA.
AC A0A151IE93;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
GN ORFNames=ALC62_10300 {ECO:0000313|EMBL:KYM99001.1};
OS Cyphomyrmex costatus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Cyphomyrmex.
OX NCBI_TaxID=456900 {ECO:0000313|EMBL:KYM99001.1, ECO:0000313|Proteomes:UP000078542};
RN [1] {ECO:0000313|EMBL:KYM99001.1, ECO:0000313|Proteomes:UP000078542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MS0001 {ECO:0000313|EMBL:KYM99001.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYM99001.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Cyphomyrmex costatus WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU910716}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00006210}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC ECO:0000256|RuleBase:RU910716}.
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DR EMBL; KQ977890; KYM99001.1; -; Genomic_DNA.
DR STRING; 456900.A0A151IE93; -.
DR Proteomes; UP000078542; Unassembled WGS sequence.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR InterPro; IPR019680; Mediator_Med1.
DR InterPro; IPR018629; XK-rel.
DR PANTHER; PTHR12881; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1; 1.
DR PANTHER; PTHR12881:SF10; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1; 1.
DR Pfam; PF10744; Med1; 1.
DR Pfam; PF09815; XK-related; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000078542};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|RuleBase:RU910716};
KW Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT TRANSMEM 33..62
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 102..121
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 133..154
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT DOMAIN 850..1208
FT /note="Mediator complex subunit Med1"
FT /evidence="ECO:0000259|Pfam:PF10744"
FT REGION 270..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 704..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1372..1717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1735..1999
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2048..2070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2091..2115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2248..2305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2358..2417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1372..1406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1417..1434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1435..1455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1465..1538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1572..1634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1646..1717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1735..1784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1824..1875
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1907..1957
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2249..2300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2364..2384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2430 AA; 260304 MW; A2B88B35BC8F12C6 CRC64;
MYNINRERSS VTWVALALQA VWRSGMLLSR VVVLVLALIF LKAWFFLFLG LHWLSMTVWV
ILQKTKFCST AWEERIYNCV IGLIYCFDFF NLRDDRSRYR VLIFYSVVAA QNLFFLIMYI
LHFGGTIESI TMIMIVSVII GFMLISLASM SLYYGKFHPS KTTTNISRNI SEHSTITKVD
ASRSFKLFHR DSLVSLHHSM DISPKTEEVP TDKQSLLTNI AQISDCVEEG IVNCNYSSEN
ESNASALRLS TECERPHSRV GVKHKEEVTS VNDNPDNVTT SSAPLNSPYS GLPDIDSSRK
RRGIYEHDIT PQLDWHAPDI LNINLDKLGF DNCERSNSLT LDSCSKVIGA LDIIKNREKL
TTPTPLESSR IFDIEKQRDE TMSCVTSIHD YENVCPLGIA RPPWCIRSWK GYTDIETYIH
DDSVVRDRRR DTLTSTTGTT YSSEYSDGMI SRGILKQDDY ADALTYDLVE SKGNKSSYGD
STFSTSADDQ NASLYVAKPV VFDDRGGMLA LDTILEERDD LSDEKFQHGT EPSRDSASTL
VSTIDQIRRY TADNSPRHIY HTTGTHWEDL NPKNLMTQAR FAKVLFNNDL RNASTTTGSI
DLTAWDVEKR EIDAFREFVR CCAIESIKKT PLIDAVLSDS PILDKASKLM RQVTFADCKN
DFDTNESDLY VEMSPLVSVE NGDNLCQARS IDAKTAETES VIKRNTLPTV SKKSPNKENL
SPSLSNNNRQ INNIDDNRDN NDSHAWTIEK DEKTDKSLCN MRFNLKEKRH LFLEQVLSPV
PKLWNKPGQP SPGGGPASDK GKEWQMEFLM EKLRSKSSTY KPLVETAKNM RMAMLDKRFA
IDSIEKNQLQ KCLDTLQHSI KVTSFQSMVE RLESLARQLG LKFMMSGPPG TEIFISSDMF
FLEVLLEPPS GLVRDVKIHH EGKSEQQSCE ALASALSRGD FVDFTTQLEG LASIYQLNAD
KKVKCKAFSA LQSLEADLGV LAQLQTFMKE PFNLVHKSPV GILERRRGGH PMKLTYFVSP
YDLIDEENRT YDTLNPDTII KRKIGHSVTV CMEGSTGHKL PTSSIITVNR SPTGKSTPSY
APLTSTNSSM LPACFVLKLV KKMPICMELV KRIQKVTELE CGDISAPHPL LSLIIQHASD
GQLDCRNNRG LYVTLPDQQH CYFMTENKNM EGVLVCSIPF THPAHVPQIL VYLRQQALFN
CLIASCVRPM ARQDPEHTTI LEVSALSWQH ISVSVEHPYE ETMATAELDL TDISTLKCRL
YGVSMTTNAE QTSDLSGRVL QRCLSIPLTM RMLLKIWEGR SLPAVMNSLT SGSGSSNGSY
NLNLGSGLPV PPSVSITPIS CGNLDQASTT NYNSVLTGMG LERRPGIEII PIASSPSQTN
LPSSITITPI AGPTSSPKTS GLTSATEDRQ RSERKSGGGK SSSSSSSKSS SEDIKSGGNK
LEKRRKRKRE DGGPMGPPEK VPSSGKQQDP LSKPVSVSIK PSPEQSPPSG GSTGVGLSCS
SSRPTSPAAV RKFSPSPTHS SSLATLVGKS SPTLKAGQSA AATCGKPVQS PKHSPVYGST
VSVPVPVPAS ASPKHGNTSS PKHGSSAASS GKPSMSALKS AANSPSSKTS SSSSSDSTTT
SSKVKSSSSS SSKDSSGRGD KDRRTSSVSS SGGSGGGHQS PKTKSSSGKM KQLEMISPSS
EAQVSSLQAS GGSTPPSGQV DAASKSAIAA QQARNRKSSL NAVIDKLKNA QHCTETDVCG
NGGSNVKGSG SSGLSGTGGM SSAGQKEKNI GGGGSSSSSG GKTIGEGGKS CVTKNASVDT
KNPAEYMVKH SSDGIKITIN KTRTKDSKQA ANLKLSSSGS MAATSSSSSL SSVASSSSSN
VIIGSNGSPK THTGLKPGVN SGPASKKPQT LQAAQKMLPT KMMLAAGMKS TISSGTTNTG
SGAGITATTT GGIGGNPLSK SGSSKASGSP KTSSGVTDLS RGRDKPRIPK SGDKGIFASK
GLGDARKSSP SALREESESE RAFKLLAAHA SISSLSPSLP PQLMMEGLMK QLDTKFQIPK
LSARANVADA DKNKSSDKLS VLSDSSKQTL DGLKQEQGKI AGLSNVTVSI SKSSLPDDQS
RRDHSQNKSD NLSITTSATG AMSLNLVGEN TGLMLPPQST ADSDVPTNLC IQPMDNEPSR
DSCKDLGMRQ TSTGQQFLGK MDDTSAGGIL SKSNVSDQLA SSGAKSYGTM TSTSTASSGA
IVTESLNLST KPADQAVLQT KYNKITVEEK KQQQTSSASL SSTSSTSSSS SSSIFSSLTS
VGTSSDGNSV MTSDSGSGGG SGGGEQEVAA AAAAAAAEML LDFSAANKDS LTKGSHGLPA
SLTQHHLTTI PERAMTQAAQ TVRRNTPPPP PPPPPLPAPF PPAASPSVSV HIVKSPAPSP
RVIPPSPHSS ASPCITDDEL MDEALVGMGK
//
