ID   A0A151IJ38_9HYME        Unreviewed;      1003 AA.
AC   A0A151IJ38;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Ubiquitin carboxyl-terminal hydrolase 8 {ECO:0000313|EMBL:KYN02885.1};
GN   ORFNames=ALC62_06283 {ECO:0000313|EMBL:KYN02885.1};
OS   Cyphomyrmex costatus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Cyphomyrmex.
OX   NCBI_TaxID=456900 {ECO:0000313|EMBL:KYN02885.1, ECO:0000313|Proteomes:UP000078542};
RN   [1] {ECO:0000313|EMBL:KYN02885.1, ECO:0000313|Proteomes:UP000078542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MS0001 {ECO:0000313|EMBL:KYN02885.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYN02885.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Cyphomyrmex costatus WGS genome.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ977412; KYN02885.1; -; Genomic_DNA.
DR   RefSeq; XP_018395321.1; XM_018539819.1.
DR   AlphaFoldDB; A0A151IJ38; -.
DR   STRING; 456900.A0A151IJ38; -.
DR   GeneID; 108773868; -.
DR   OrthoDB; 227085at2759; -.
DR   Proteomes; UP000078542; Unassembled WGS sequence.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   GO; GO:0019538; P:protein metabolic process; IEA:UniProt.
DR   CDD; cd02674; Peptidase_C19R; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR   Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR001763; Rhodanese-like_dom.
DR   InterPro; IPR036873; Rhodanese-like_dom_sf.
DR   InterPro; IPR015063; USP8_dimer.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   PANTHER; PTHR21646:SF104; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   Pfam; PF00581; Rhodanese; 1.
DR   Pfam; PF00443; UCH; 1.
DR   Pfam; PF08969; USP8_dimer; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR   SUPFAM; SSF140856; USP8 N-terminal domain-like; 1.
DR   PROSITE; PS50206; RHODANESE_3; 1.
DR   PROSITE; PS00972; USP_1; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:KYN02885.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078542}.
FT   DOMAIN          169..292
FT                   /note="Rhodanese"
FT                   /evidence="ECO:0000259|PROSITE:PS50206"
FT   DOMAIN          669..998
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
FT   REGION          331..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          388..413
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          592..641
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        388..408
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        598..614
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        627..641
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1003 AA;  115734 MW;  C43937CAE93B37B5 CRC64;
     MSNATNLMYT SINDLVQKAK INYTGKEPRN VYQRLPAMRQ NSDLAKKQGD DEKAYIFLKR
     WLDSVEWLKR THNKDGKSAY AASMTVEQIN EAKNILADLK QKLEVRYKLN SKKCNDKVEL
     MEVEMDESKA PNSDIGLKLP EIPAEDISLS SDSDNFISCD KLYNLIQKIR ARYLIIDTRQ
     TAHYENSRIS SDRCINIPQS EIKRGLLGTH FEKYFANDKH SYDLFVNRSA QHTDILVLLD
     WNTTQETLTP YIHINLLKDI FEKWDPGIKH KKIKILNGGY QEWLERYPAF TTNPSIEVPE
     FKTVTLDEKI LDTFEYPSWA CSDSEEEILK KGKDEQETKS ELNNMSDSNV DMEIDHGDNK
     SAISRHARSN SNDTISSTKS KNFVNHITIS INDKRPSRSD SVNGQRLESP ESPVLAHSKI
     LSNKMPQNEV SAKPMIDRSS KPTALKTYDP RCKEVLKFMK ELNELAKSKS KLATELLTQE
     YELYSQRENK YSLSDEKYLR TEIKSLKVKL EDMHKMYLKI ENEFKTYLKE TDTIKFNSTD
     DYEKKNLEFN LCLLNNEIKD IETKRKKLQE DFLQRGHKEI LKNDSDVYKE PLKDGSSINT
     GLERSYSSPN LLQLGDRKAP QIDRTSKPHI SPRNQNGIGN ENIKVSSLSW GNREERMTPI
     HGTVHPGITG LKNLGNSCYM NSIIQCLSNT TNLAKYFIDN SYADDLNTNN DNITQGQVVE
     EVAQVIKALW RGQYKSISPY DLKVAVGQYK LQFESYEQQD SHEFLMFLLD WMHNELKKNM
     KMPIEMTNAE KEWDKAMNSQ RSIISDLFFG QLRSTITCSF CKQASTTYET FNTLPMSLSQ
     SNRCTLNDCM EKFVTGQKVS GWKCSKCQTP RDATKKFDFV KLAPIVVIHL HRFAESGGWL
     EKRNTAVDFP LTGFNLKPYL VLENTKAIMS NNIRNYNYTL YAISNHYGTM DGGHYTAFCK
     NSTQNKWYKY DDQTVTEVSP SQVKSQNTSA YLLFYTSFPN TIM
//