ID   A0A151IMN5_9HYME        Unreviewed;      1402 AA.
AC   A0A151IMN5;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   22-FEB-2023, entry version 26.
DE   SubName: Full=Calcium-dependent secretion activator {ECO:0000313|EMBL:KYN06215.1};
GN   ORFNames=ALC62_02807 {ECO:0000313|EMBL:KYN06215.1};
OS   Cyphomyrmex costatus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Cyphomyrmex.
OX   NCBI_TaxID=456900 {ECO:0000313|EMBL:KYN06215.1, ECO:0000313|Proteomes:UP000078542};
RN   [1] {ECO:0000313|EMBL:KYN06215.1, ECO:0000313|Proteomes:UP000078542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MS0001 {ECO:0000313|EMBL:KYN06215.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYN06215.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Cyphomyrmex costatus WGS genome.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ977026; KYN06215.1; -; Genomic_DNA.
DR   STRING; 456900.A0A151IMN5; -.
DR   Proteomes; UP000078542; Unassembled WGS sequence.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0098793; C:presynapse; IEA:GOC.
DR   GO; GO:1990504; P:dense core granule exocytosis; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:InterPro.
DR   CDD; cd01234; PH_CADPS; 1.
DR   Gene3D; 1.10.357.50; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR033227; CAPS.
DR   InterPro; IPR010439; MUN_dom.
DR   InterPro; IPR014770; Munc13_1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR12166; CALCIUM-DEPENDENT SECRETION ACTIVATOR; 1.
DR   PANTHER; PTHR12166:SF8; CALCIUM-DEPENDENT SECRETION ACTIVATOR; 1.
DR   Pfam; PF06292; MUN; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM01145; DUF1041; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51258; MHD1; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000078542};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   DOMAIN          440..554
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          580..690
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          982..1113
FT                   /note="MHD1"
FT                   /evidence="ECO:0000259|PROSITE:PS51258"
FT   REGION          1..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          422..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        103..139
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        140..155
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1402 AA;  158073 MW;  58ECE79A7D36ECC8 CRC64;
     MIDPSSSEEE SEEDQSTHHG SGGGGSAGGR AGSGSSHGSR RHPGSIGNGP GSGSVGSLAS
     SLTASPGGPN HVSAPSTAST HGSGSRVTAG PQETAGVGLD VPNLTSARNS LSPSMSATQD
     ASNYAQRPTS PSPSVASEKT EAELQDKQER EEEQRKTRIQ LYVFISRCIA YPFNAKQPMD
     MTRRQMKVTK QQLETICSRF QSFLKGETQI MADEAFHNAI QNYYDVFLKS DRVVQMVQSG
     ACSQLDFREV FKKNIDKRVR SLPEIDGLSK ETVLTSWLAK FDCILKGTGD EDTKRPSRMQ
     QQSLNSELIL SKEQLYDMFQ QILGIKKFEH QLLFNALLLD SADEQAAAIR RELDGRVQKV
     NEMEKNRKLM PRFLLKEMES LYIEELKSSI NLLMTNLESL PVSKGSIDSK YGLQKLKRYN
     HRGERSRCRG QGSLAKLEGD SADSDPQLTK MDVGLTFQLE VVVMEVKGLK SLAPDRIVYC
     TMEVEGGEKL QTDQAEASKP MWDTQGDFTT MHPLPVVKVR LYTENPAMLA LDDKELGKVI
     LRPTPLSCKT PEWHRMNVPK NCADQDLRMK IACRMDKPLN MKHCGYLYAM GKSVWKKWKK
     RYFVLVQVSQ YTFAMCSYKE KKSEPSEMMQ LDGYTVDYIE AVSANLMVGM DLEGGRYFFN
     AVREGDNIVY ASDDENECHL WVMAMYRATG QSHKPTPPVS VADKNSTISK IQGDADRAKK
     HGMEDYISAD PCKFDHHGLF KYLQNLILDY RLNDPYCSLG WFSPGQVFVL DEYCARYGVR
     GCFRHLCYLH DLLDRIDRGI MIDPTLIHYG FAFCATHVYG NTTSADGVGS ITHEEKDKFQ
     EIKERLRQIL ENQITNFRYS FPFGRPEGAL KATLSLLERV LMKDSVTPVP QEEVKALIKN
     CLETAALVNY TKLSAEAKIE DDLSGEVCVP PSKKLEDLIH LAELCVDLLQ QNEEHYSETV
     AFAWFSDLMV EHAEIFWSLF AVDMDKVLAE QPPDTWDSFP LFQIMNDYLK TDDNLKNGRF
     HQHLRDTFAP LVVRYVDLME TSIAQSIHKG FEKERWEIKG NGCATSEDLF WKLDALQSFI
     GGLHWPDQEF RQHLEQRLKL MACDMVESCI QRTDAAFQQW LKKGVTFIST DYIIPSEMCA
     MVNVILDAKN QSFKLCTVDG VDVHQYHSKI DDMIEKTSAG MNQGMINKLI TVLEATLSKL
     SRYDEGSLIG SILSLTKVSG SGKEMGQAYV NFMRNCIDQI RSKVLDELWI LTFFEQWYTA
     QIQMLCNWLS ERLDHSLHLY QCTCLAHIVK KIYSDFELQG VMEEKLNTKT YQTIDKRMKT
     EEATCALTMS AQNEEGLSEN GNDDEVERPK TKVTIVETIT EDANYVANLS NVTSNVVGKV
     GSMFGKGIGG LSTKFGSASN WF
//