ID   A0A151JEH4_9VIBR        Unreviewed;       660 AA.
AC   A0A151JEH4;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:KYN24174.1};
GN   ORFNames=AUQ44_20905 {ECO:0000313|EMBL:KYN24174.1};
OS   Vibrio cidicii.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=1763883 {ECO:0000313|EMBL:KYN24174.1, ECO:0000313|Proteomes:UP000075349};
RN   [1] {ECO:0000313|Proteomes:UP000075349}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2756-81 {ECO:0000313|Proteomes:UP000075349};
RA   Tarr C.L., Gladney L.M.;
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KYN24174.1}.
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DR   EMBL; LOMK01000002; KYN24174.1; -; Genomic_DNA.
DR   RefSeq; WP_065820297.1; NZ_MPKQ01000034.1.
DR   AlphaFoldDB; A0A151JEH4; -.
DR   Proteomes; UP000075349; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR033417; CHASE8.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR   PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF17152; CHASE8; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        167..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          186..239
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          251..323
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          366..436
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          524..656
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   660 AA;  73805 MW;  039B941ACAC7A255 CRC64;
     MPSLKNLSIR HKLLVPILIF VTFIFIFAQG FHFFVNYQNE QKNLIDRVSI LAKGVAFNLQ
     AAVLFDDSLA ASEVLSAFNA DPAILRVKLF DLNEQLFSIY EAQADEAPIP DQTQRDALQK
     KGHLVAGKYL YLLVPIEMDG SKIASLRITV SNQAFEQIIN KLIESSIVFL FMLLPTGALL
     YLIVQKFILE PVYSLHDSMQ AFVEHRLKRP NLKPKADDEI GALIDAFNTM VKRLAQRDSQ
     VHYTLDRLEK EKAFANEVIE TVQHALLVVN HDGVILHSNA ASKEIFPISL AAVENNTLTD
     LIQTEEKAVL IAAIEQKQVL DDYLLSCKKA DQSVQLLQIS SRSISNRGAT LFAIQDVTEI
     EAAMNRQRIA AGVFEHSQDG LIVLDHNGVI TMCNPALTHM LGYSSDTLVG RSFLQVFHWK
     QLQSLMPTIQ ESLAHYGQWQ GEVWEKHLNG TLVPMFAKVS HIVKKVDQEE VYDMVIILAD
     LSDAKEMERL EYLAHHDALT GLANRSKLHR ILEEELRSSA YSNKELALLY MDLDGFKQVN
     DTFGHDAGDE VLRVISTRLQ QEVRSSDLVA RLSGDEFVLL VKPASPQSVT QLTERLLQSI
     CRPIQYNGQT LQVGCSIGVK LIGSNEKDMD NILKCADTAM YRAKKAGKGQ AIVIGAAVSD
//