ID A0A151JVC3_9HYME Unreviewed; 2070 AA.
AC A0A151JVC3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Eukaryotic translation initiation factor 3 subunit B {ECO:0000256|HAMAP-Rule:MF_03001};
DE Short=eIF3b {ECO:0000256|HAMAP-Rule:MF_03001};
DE AltName: Full=Eukaryotic translation initiation factor 3 subunit 9 {ECO:0000256|HAMAP-Rule:MF_03001};
GN ORFNames=ALC56_08214 {ECO:0000313|EMBL:KYN37426.1};
OS Trachymyrmex septentrionalis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=34720 {ECO:0000313|EMBL:KYN37426.1, ECO:0000313|Proteomes:UP000078541};
RN [1] {ECO:0000313|EMBL:KYN37426.1, ECO:0000313|Proteomes:UP000078541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tsep2-gDNA-1 {ECO:0000313|EMBL:KYN37426.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN37426.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex septentrionalis WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: RNA-binding component of the eukaryotic translation
CC initiation factor 3 (eIF-3) complex, which is involved in protein
CC synthesis of a specialized repertoire of mRNAs and, together with other
CC initiation factors, stimulates binding of mRNA and methionyl-tRNAi to
CC the 40S ribosome. The eIF-3 complex specifically targets and initiates
CC translation of a subset of mRNAs involved in cell proliferation.
CC {ECO:0000256|HAMAP-Rule:MF_03001}.
CC -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03001}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03001}.
CC -!- SIMILARITY: Belongs to the IFT172 family.
CC {ECO:0000256|ARBA:ARBA00038130}.
CC -!- SIMILARITY: Belongs to the eIF-3 subunit B family. {ECO:0000256|HAMAP-
CC Rule:MF_03001}.
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DR EMBL; KQ981706; KYN37426.1; -; Genomic_DNA.
DR STRING; 34720.A0A151JVC3; -.
DR Proteomes; UP000078541; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR CDD; cd12278; RRM_eIF3B; 1.
DR Gene3D; 1.25.40.470; -; 3.
DR Gene3D; 1.25.40.980; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR HAMAP; MF_03001; eIF3b; 1.
DR InterPro; IPR011400; EIF3B.
DR InterPro; IPR034363; eIF3B_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR013979; TIF_beta_prop-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15722; IFT140/172-RELATED; 1.
DR PANTHER; PTHR15722:SF2; INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG; 1.
DR Pfam; PF08662; eIF2A; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF69322; Tricorn protease domain 2; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03001};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540, ECO:0000256|HAMAP-
KW Rule:MF_03001};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917, ECO:0000256|HAMAP-
KW Rule:MF_03001}; Reference proteome {ECO:0000313|Proteomes:UP000078541};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_03001}; TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 64..149
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..40
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2070 AA; 232424 MW; 864D16D278B35004 CRC64;
MAKKTQAEKT AQNDETVKGN DDPMNDDEEP NFSDPEGFVD DITDEELLGD ILKQKPSETD
GVESVIVVDN VPRVEPDKLE KLQSVINKVL GKFGTIVNQY YPMNETDGKT KGYIFLEYNN
HLNALTAVKS TNNYKIDKSH TFKVNLFTDF KKFEDIPENW EPPKAQPFKA ASDLHYHLLE
PDAYDQFCVL CGNGAGVSVQ IWQNSAPEPT SLEERNRWTE TYVKWSPLGT YLSTFHKLGV
ALWGGPQFTQ QARFSQRGVE CIDFSPCERY LVTYTPRTDL GQDQKRLVIW DILSGQEKRS
FFPDGSSVWP IFRWSHDDKY LARMGEDILS VYETPSFGLL DKKSIKIPGI RDFSWSPTDN
VLAYWVPEDK DVPARVTLLE IPNRNEIRNK NLFNVADCKI FWQKSGDYLC VKVDRFAKHY
SHFTLQGMSY NFEIFHMREK QIPVDSVEIK EPIHAFAWEP VGSKFAIIHG EIPSVNVSFY
EVRYGHQPAL LKRLEKKACN HLFWSPSGQF IVLAGLTTMA GALEFIDTND FTIMNSTDHY
QTSDVEWDPT GRYVVTAVSS WKTSVDNGYW IWTFQGRILK RVNLTAFNQL LWRPRPPTLL
TAEQIKEIKK NLKKYSAQFE SKDRMRLTRA SKFGKKSYLV KGIAFSPEST KIAVGQTDCI
VYVYKIGEDW GDKKVICNKF RQSAAVTCLI WPVDGPIIVG LADGKVRAAM IKSQKTQTLY
TSDAMTIALA SNVRGSGFLS GHADGSIIRY YIVEDGNAEP SGRVCVHGVP PYALAWPQSH
ILAAGCDKRL TMYDPYGKPV KTFDFSRDFQ EREITVACCS PSGQSVAVGS WDKVRIFDWS
PRRSIWEETN VRDLPNFYTV TALSWRRDGS KLIVGGLCGS VEQFETILRR TVVRGSHEVA
YVGPSQVVIR PLSDSSQRPI VIRSQTGLEI EDVRVLGRRD NNVVARTART LLIGDIELGL
ISEIPWEDRS GGEKFFFEYP VVCLIFCSGE LTIVEYGQNE ALGSVRTEAV NPHVVSVRVN
ERLSSGGGDN KKLAYLLDPR TVRVIDLLSG ATISMIVHDA RIDWLELSEA GHKLLSRDKR
GRLWLSDDEG DKVLLVTGVS FASWVTGSDV VVAQTGQTLA VWYNVDAPEA ITLTSIKGDV
VDIVREDNRT SVMVEEHGGI KVAHQLDEGL IEFGTALHDN DFGRVILFLE NMGDGPQVET
MWENVARNAM NERKLDIAAR CYAAMGDVAC AKFLKEIAEI GEKYAKETGN EPMANPECWA
RLAVLNGDLK TAEAIYLEQN ELDKALDMYQ RYWRWEDALN LAESRSWSGL SELRDRHLAW
LLDTGQAARA ASIIETTNPR RAVKLYLEAR RPGRAARLIL ADNELLEDER IVEEVISGLK
ATDLAELAGE LLEKTGAGSE AIKCYSQAGV FARALDLARK IDPTLVVELE RDWGKHLSEN
GHYDAAINHF IEAGETVLAL KAAINARQWR KALQIIQVIE DDNPEIRQQC EKLGEYFSSI
GERSLAESLF IRAENAQRAV EIHIQSGDWI RAHQVAQEHM KSDEANQVLA KHAESLQQNG
ELRHAESLYV AIGDHDAAIA MYRKAGNRSD MVRLVAQHRP DLLQTTHQHL ARELDAAGKA
REAEEHFLGA GDWRGAVTAY RSANMWEDAL RVAKKASGEK AAQQVALMWA RTLAPELGAR
LLMRLSYLEP CLQLACEANL FDWALEIAKY GTVDQKKEVH YRYAMALEDE GRFVEAEKEF
VQAGKTMEAV QMYIHTRDWE SAEDVARSHS QEAVAQVLIA RAAEAAEGQD YATAEALLLR
AHKPEMIIEH YKTAGMWSEA LRVCREYLPS QEAALRRELG QRSAGLDGAN ALEEARKWLN
LGEVRPALDT LILNPQAPRS YLIRAADILL HQADPETAAE VGGDLGERLF SVGEHALAAQ
KLNSCCQTAG SRAAAATAIT WSLNERLRIA DNVDKGCARR VSTIQYRNPP PTRETLGGEA
RLYVHYVYTG TFLRNAKCRT LFGPFAKYPA DVIHPYEVSP RKLFGAFPRD FPYRPPPRLP
SGFSAVAMNP LFLLTGVSVK PPVRRALALS
//
