ID A0A151JX04_9HYME Unreviewed; 571 AA.
AC A0A151JX04;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 16 {ECO:0000313|EMBL:KYN38972.1};
GN ORFNames=ALC56_06667 {ECO:0000313|EMBL:KYN38972.1};
OS Trachymyrmex septentrionalis.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=34720 {ECO:0000313|EMBL:KYN38972.1, ECO:0000313|Proteomes:UP000078541};
RN [1] {ECO:0000313|EMBL:KYN38972.1, ECO:0000313|Proteomes:UP000078541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tsep2-gDNA-1 {ECO:0000313|EMBL:KYN38972.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYN38972.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex septentrionalis WGS genome.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00276}.
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DR EMBL; KQ981629; KYN38972.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151JX04; -.
DR STRING; 34720.A0A151JX04; -.
DR Proteomes; UP000078541; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04272; ZnMc_salivary_gland_MPs; 1.
DR Gene3D; 3.40.1620.60; -; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR006586; ADAM_Cys-rich.
DR InterPro; IPR041645; ADAMTS_CR_2.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR001590; Peptidase_M12B.
DR InterPro; IPR034030; ZnMc_salivary_gland_MPs.
DR PANTHER; PTHR11905; ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN; 1.
DR PANTHER; PTHR11905:SF243; SOL NARAE, ISOFORM C; 1.
DR Pfam; PF17771; ADAMTS_CR_2; 1.
DR Pfam; PF13582; Reprolysin_3; 1.
DR SMART; SM00608; ACR; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR PROSITE; PS50215; ADAM_MEPRO; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00023049};
KW Integrin {ECO:0000313|EMBL:KYN38972.1};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00276};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000078541};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00276}.
FT DOMAIN 42..274
FT /note="Peptidase M12B"
FT /evidence="ECO:0000259|PROSITE:PS50215"
FT ACT_SITE 204
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00276"
FT BINDING 203
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00276"
FT BINDING 207
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00276"
FT BINDING 213
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00276"
SQ SEQUENCE 571 AA; 63988 MW; 38C2B1014C6F0E0A CRC64;
MDRPISDEYS DFSLMEPDRL VKRYRIKRSI NSRSRREAPY VIYPEILCIV DYDGYRLHGG
DNVQIKRYFV SFWNGVDLRY KLLKGPKIRI SIAGIIISRG RDATPYLERN RVGRDAIDSA
AALTDMGKYL FRERRLPVYD IAVAVTKLDM CRRQYANDVC NRGTAGFAYV GGACVVNKRL
EKVNSVAIIE DTGGFSGIIV AAHEVGHLLG AVHDGSPPPS YLGGPGAEKC RWEDGYIMSD
LRHTEKGFKW SHCSVSSFHH FLNGDTATCL YNAPHEDEAL PRVLPGKLLS LDAQCRKDRG
TSACFKDDRV CAQLFCFDAG SGYCVAYRPA AEGSPCGDGQ YCLNGKCVAE HENIIPDYTQ
NIPTYVRRDS IFNSAIHTRP IFAHYNNTDY RYPWEATQSI PLSSITPSTP TTTATIRTST
YPYKHVTNLF ATTVSKYTRT IINNLYTDQY KTRYNNNNSN NSNSGTGGGF STTTRRSNFF
NSYYTVSTTP KVTYGPKVNP FKYKNTVISF STTTKGYQNG LRNDGRETEA GECTDVGSDC
AELIDRLRTW LCHLQSVKSR CCASLKTICA D
//
